M.Sc. in Agricultural Statistics
AGRICULTURAL
STATISTICS
Course
Structure - at a Glance
COURSE TITLE
- ELEMENTARY STATISTICAL METHODS
- STATISTICAL METHODS FOR RESEARCH WORKERS
- STATISTICAL METHODS FOR
BIOLOGY
- EXPERIMENTAL DESIGN FOR RESEARCH WORKERS
- STATISTICAL METHODS FOR SOCIAL SCIENCES
- TIME SERIES ANALYSIS
- LINEAR PROGRAMMING
- ECONOMETRICS
- BIOMETRICAL GENETICS
M. Sc. (Agricultural Statistics)
- MATHEMATICAL METHODS-I
- MATHEMATICAL METHODS-II
- PROBABILITY THEORY
- STATISTICAL METHODS
- STATISTICAL INFERENCE
- MULTIVARIATE ANALYSIS
- DESIGN OF EXPERIMENTS
- SAMPLING TECHNIQUES
- STATISTICAL GENETICS
- REGRESSION ANALYSIS
- STATISTICAL COMPUTING
- TIME SERIES ANALYSIS
- ACTUARIAL STATISTICS
- BIOINFORMATICS
- ECONOMETRICS
- STATISTICAL QUALITY CONTROL
- OPTIMIZATION TECHNIQUES
- DEMOGRAPHY
- STATISTICAL METHODS FOR LIFE SCIENCES
- STATISTICAL ECOLOGY
- MASTER'S SEMINAR
- MASTER'S RESEARCH
Note:
- STAT 551 and STAT 552 are supporting
courses. These are compulsory for all the students of Agricultural
Statistics.
- STAT 560 - STAT
569 are core courses to be taken
by all the students of Agricultural
Statistics.
- STAT 591 and STAT 599 are compulsory for all
the students of Agricultural Statistics.
- A student has to
take a minimum of 36 credits
course work, excluding the supporting
courses, seminar and research.
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Ph. D. (Agricultural Statistics)
- ADVANCED STATISTICAL COMPUTING
- SIMULATION TECHNIQUES
- ADVANCED STATISTICAL METHODS
- ADVANCED STATISTICAL INFERENCE
- ADVANCED DESIGN OF EXPERIMENTS
- ADVANCED SAMPLING TECHNIQUES
- ADVANCED STATISTICAL GENETICS
- STATISTICAL MODELING
- ADVANCED TIME SERIES ANALYSIS
- STOCHASTIC PROCESSES
- SURVIVAL ANALYSIS
- ADVANCED BIOINFORMATICS
- ADVANCED ECONOMETRICS
- RECENT ADVANCES IN THE FIELD OF
SPECIALIZATION
- DOCTORAL SEMINAR I
- DOCTORAL SEMINAR II
- DOCTORAL RESEARCH
Note:
- STAT 601 and STAT 602 are supporting courses.
These are compulsory for all the students of Agricultural
Statistics.
- STAT 691, STAT 692,
STAT 651 and STAT 699 are
compulsory for all the students of Agricultural
Statistics.
- A student has to
take a minimum of 18 credits
course work, excluding the supporting courses, seminar
and research.
- A student has to take two seminars.
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Elementary
Statistical Methods (For those students who do not have sufficient statistical
background)
- Probability : Elementary concepts
of probability; Addition theorem; Conditional Probability; Multiplication
theory; Independence of events.
- Statistical Methods : Population
and its parameters; Sample and its statistics; Frequency distribution;
Graphical representation; Measures of central tendency; Measures of
dispersion; Moments; Simple correlation and regression.
- Probability Distributions :
Binomial; Poisson & Normal
- Sample Survey : Elementary
concept; Advantages of sample survey over census; Simple random sampling
(SRS); SRSWR and SRSWOR; Drawing of random sample & estimation of
average, total etc.; Sampling and non-sampling errors; Concept of
stratified random sampling.
- Design of Experiments : One way
and two way classification (orthogonal); Principles of design; Uniformity
trial and fertility contour map; Lay-out and analysis of CRD, RBD and
LSD.
- Tests of Significance :
Hypotheses; Two types of errors; Exact small sample tests: z, t, χ2 and
F-tests.
- Practicals : Based on above
topics.
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Statistical Methods for Research Workers
- Probability : Elementary concepts
of probability; Addition theorem; Conditional Probability; Multiplication
theory; Independence of events.
- Statistical Methods : Population
and its parameters; Sample and its statistics; Frequency distribution;
Graphical representation; Measures of central tendency; Measures of
dispersion; Moments; Simple correlation and regression.
- Probability Distributions :
Binomial; Poisson & Normal
- Sample Survey : Elementary
concept; Advantages of sample survey over census; Simple random sampling
(SRS); SRSWR and SRSWOR; Drawing of random sample & estimation of
average, total etc.; Sampling and non-sampling errors; Concept of
stratified random sampling.
- Design of Experiments : One way
and two way classification (orthogonal); Principles of design; Uniformity
trial and fertility contour map; Lay-out and analysis of CRD, RBD and
LSD.
- Tests of Significance : Hypotheses;
Two types of errors; Exact small sample tests: z, t, χ2 and F-tests.
- Practicals : Based on above
topics.
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Statistical Methods for Research Workers
- Probability and
- Distribution : Preliminaries;
Bayes' theorem; Repeated trials; Random variable- Mathematical expectation
and its laws; variance, covariance etc.; Distribution: Binomial, Poisson,
Normal.
- Statistical Methods : Rank
correlation; Correlation ratio; Intra-class correlation; Multiple
Regression involving three variables; Multiple and partial correlation
co-efficients; Stepwise multiple regression analysis; Concept of
auto-correlation function (ACF).
- Tests of Significance : t, F, χ2
-tests and large sample tests; Confidence intervals; Transformation of
Variables: Z-transformation.
- Sample Survey : Stratified random
sampling; Systematic sampling and cluster sampling.
- Design of Experiments : LSD; Uses
of repeated Latin squares; Missing plot techniques in RBD and LSD;
Split-plot design; Multiple comparison tests.
- Practicals : Based on above
topics.
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Statistical Methods for Biology
- Probability and
- Distribution : Random variable and
its expectation, variance etc., Binomial Poisson, Normal, Negative
Binomial and Log normal distributions.
- Statistical Methods :
Multiple and partial correlation; Multiple
regression;
- Reproduction and mortality rates and their estimation;
Techniques for estimation of population number and growth.
- Tests of Significance : Z, t, F
and χ2 -tests.
- Design of Experiments : CRD, RBD
and LSD and Split-plot design; Multiple comparison tests; Missing plot
techniques in RBD and LSD; Elementary bio-assay and probit analysis.
- Practicals : Based on above
topics.
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Experimental Design for Research Workers
- Uniformity trails : Size and shape
of pots and blocks; Lay-out and analysis of CRD and RBD; Use of Repeated
LSD's; Efficiency of blocking; Missing plot techniques and analysis of
covariance in RBD and LSD Multiple comparison tests.
- Factorial Experiments :
Interpretation of main effects and interaction; Orthogonality and
partitioning of degrees of freedom; Analysis of 22, 23, 32 experiments;
Concept of confounding and analysis of some confounded factorial
experiments; Split plot and strip plot designs; Transformations; Analysis
of groups of experiments.
- Practicals : Based on above
topics.
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Statistical Methods for Social Sciences
- Introduction : Frequency
distribution; Principles governing their formation and standard
distributions.
- Concept of Sampling : SRS and
stratified random sampling; Sampling and nonsampling errors and their
remedial measures.
- Praticals : Based on above topics.
- Tests of Significance : t, F, χ2
-tests and large sample tests; Confidence intervals;
- Transformation of Variables; Z-transformation;
Distributionfree statistics- run test, sign test; Wilcoxon sign-rank test,
Mann-Whitney U-test; Wald – Wolfowitz run test; Median test etc.
- Statistical Methods : Simple and
multiple regression and prediction equations.
- Application of
- Multivariate Analysis : Factor
analysis, Cluster analysis; Discriminant function and D2 statistics;
Principal component analysis.
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Time series Analysis
- Time series and its components; Estimation/Elimination
of different components; Variate-difference method. Concept of harmonic
analysis; Correlogram and periodogram analysis; Introduction of spectral
analysis; Economic application of multivariate time serice; Forecasting:
Concept and different methods.
- Practical : Based on above topics
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Linear Programming
- Convex sets; Programming problems; Graphical
methods and simplex method for solution; Duality in liner
programming; Revised simplex and dual simplex method; Transportation and
assignment problems. Introduction to integer programming; Quadratic
programming and their application and uses. Elements of game theory; two
person-zero-sum game; Relationship between game theory and linear
programming.
- Practical: Based on above
topics
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Econometrics
- Classical Linear Regression Models
: Assumptions; BLUE and least square
estimates and their properties; Prediction
problems.
- Autocorrelation and Heteroscedasticity
: Definition; Causes of such problems and their remedies.
- Multicollinearity : The
meaning and consequences of its existence; Tests
of identifying the existence of multicollinearity; Remedies
necessary for analysis.
- Simultaneous Equation Models :
Definitions; OLS; ILS, 2 SLS methods
and their applications.
- Practicals : Based on above
topics.
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Biometrical Genetics
- Estimation of linkage
from back-cross; F2 and F3 data
using method of MLE and other methods;
Disturbed segregation; Estimation of additive
genetic dominance and environmental components of variation;
Plant Breeding trials and their use in the estimation of genetic variation
and variability; Simple ideas of discriminant function for plant
selection. Path analysis; Genotypic correlation; Path coefficients. North
– Carolina Mating Designs; NC Design I, II, III, Line X Tester design
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MATHEMATICAL METHODS - I
Objective
- This course lays the
foundation of all other courses
of Statistics/ Agricultural Statistics discipline
by preparing them to understand the
importance of mathematical methods in research. differential equations
and numerical analysis. This would prepare them to study their main
courses that involve knowledge of Mathematics.
Theory
- UNIT I
- Real Analysis: Convergence
and divergence of infinite series, use
of comparison tests -D'Alembert's Ratio
- test, Cauchy's nth root test,
Raabe's test, Kummer's test, Gauss
test. Absolute and conditional convergence.
Riemann integration, concept of Lebesgue integration, power
series, Fourier, Laplace and Laplace
-Steiltjes' transformation, multiple integrals.
- UNIT II
- Calculus: Limit and
continuity, differentiation of functions,
successive differentiation, partial
differentiation, mean value theorems, Taylor
and Maclaurin's series. Application of derivatives, L'hospital's
rule. Integration of rational,
irrational and trigonometric
functions. Application of
integration.
- UNIT III
- Differential equation: Differential equations
of first order, linear differential equations of higher order with
constant coefficient.
- UNIT IV
- Numerical Analysis: Simple interpolation,
Divided differences, Numerical differentiation and
integration.
Suggested Readings
- Bartle RG. 1976. Elements of Real Analysis.
John Wiley.
- Chatterjee SK. 1970. Mathematical Analysis.
Oxford & IBH.
- Gibson GA. 1954. Advanced Calculus.
Macmillan.
- Henrice P. 1964. Elements of Numerical
Analysis. John Wiley.
- Hildebrand FB. 1956.
Introduction to Numerical Analysis. Tata
McGraw Hill.
- Priestley HA. 1985. Complex Analysis.
Clarendon Press.
- Rudin W. 1985. Principles of Mathematical
Analysis. McGraw Hill. Sauer T. 2006. Numerical Analysis With
CD-Rom. Addison Wesley.
- Scarborough JB. 1976. Numerical Mathematical
Analysis. Oxford & IBH. Stewart J. 2007. Calculus.
Thompson.
- Thomas GB Jr. & Finney RL. 1996. Calculus.
9th Ed.
Pearson Edu.
********************************
MATHEMATICAL METHODS - II
Objective
- This is another course
that supports all other courses in Statistics
/
- Agricultural Statistics. The students would be
exposed to the advances in Linear Algebra and Matrix theory. This
would prepare them to study their main courses
that involve knowledge of Linear Algebra
and Matrix Algebra.
Theory
- UNIT I
- Linear Algebra: Group,
ring, field and vector spaces,
Sub-spaces, basis,
- Gram Schmidt's
orthogonalization, Galois field - Fermat's
theorem and
- primitive elements. Linear
transformations. Graph theory: Concepts and
applications
- UNIT II
- Matrix Algebra: Basic terminology, linear
independence and dependence of vectors. Row and
column spaces, Echelon form. Determinants,
rank and inverse of matrices. Special matrices - idempotent,
symmetric, orthogonal. Eigen values and eigen vectors. Spectral
decomposition of matrices
- UNIT III
- Unitary, Similar, Hadamard, Circulant,
Helmert's matrices. Kronecker and Hadamard product
of matrices, Kronecker sum of
matrices. Sub-matrices and partitioned
matrices, Permutation matrices, full rank
factorization, Grammian root of a
symmetric matrix. Solutions of linear
equations, Equations having many solutions.
- UNIT IV
- Generalized inverses,
Moore-Penrose inverse, Applications of
g-inverse. Spectral decomposition of
matrices, Inverse and Generalized inverse
of partitioned matrices, Differentiation and integration of
matrices, Quadratic forms.
Suggested Readings
- Aschbacher M. 2000. Finite Group Theory.
Cambridge University Press.
- Deo N. 1984. Graph
Theory with Application to Engineering
and Computer Science. Prentice Hall of India.
- Gentle JE. 2007. Matrix Algebra: Theory,
Computations and Applications in Statistics. Springer.
- Graybill FE.1961. Introduction to Matrices
with Applications in Statistics. Wadsworth Publ.
- Hadley G. 1969. Linear Algebra. Addison
Wesley.
- Harville DA. 1997.
Matrix Algebra from a Statistician's
Perspective.
- Springer.
- Rao CR. 1965. Linear
Statistical Inference and its Applications.
2 nd Ed. John Wiley.
- Robinson DJS. 1991. A Course in Linear Algebra
with Applications. World Scientific.
- Searle SR. 1982. Matrix Algebra Useful for
Statistics. John Wiley.
- Seber GAF. 2008. A Matrix Handbook for
Statisticians. John Wiley.
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PROBABILITY THEORY
Objective
- This is a fundamental course in Statistics.
This course lays the foundation of probability
theory, random variable,
probability distribution, mathematical expectation,
etc. which forms the basis of basic statistics. The students
are also exposed to law of large
numbers and central limit theorem. The students
also get introduced to stochastic processes.
Theory
- UNIT I
- Basic concepts of
probability. Elements of measure theory:
class of sets, field, sigma field,
minimal sigma field, Borel sigma field
in R, measure, probability measure.
Axiomatic approach to probability.
Properties of probability based on
axiomatic definition. Addition and
multiplication theorems. Conditional probability
and independence of events. Bayes theorem.
- UNIT II
- Random variables: definition of random
variable, discrete and continuous, functions of
random variables. Probability mass function
and Probability density function, Distribution
function and its properties. Notion
of bivariate random
variables, bivariate distribution
function and its properties.
Joint, marginal and conditional distributions. Independence of
random variables. Transformation of random
variables (two dimensional case only).
- Mathematical expectation:
Mathematical expectation of functions of
a random variable. Raw and central moments and their
relation, covariance, skewness and kurtosis.
Addition and multiplication theorems
of expectation. Definition of
moment generating function, cumulating
generating function, probability generating function and statements of
their properties.
- UNIT III
- Conditional expectation and
conditional variance. Characteristic function
and its properties. Inversion and
uniqueness theorems. Functions, which cannot be
characteristic functions.
- Chebyshev, Markov,
Cauchy-Schwartz, Jenson, Liapounov, holder's
and Minkowsky's inequalities. Sequence of
random variables and modes of convergence
(convergence in distribution, in probability, almost surely, and
quadratic mean) and their interrelations.
Statement of Slutsky's theorem. Borel -Cantelli
lemma and Borel 0-1 law.
- UNIT IV
- Laws of large numbers:
WLLN, Bernoulli and Kintchin's
WLLN.
- Kolmogorov inequality, Kolmogorov's
SLLNs.
- Central Limit theorems: Demoviere-
Laplace CLT, Lindberg - Levy CLT, Liapounov CLT,
Statement of Lindeberg-Feller
CLT and simple applications.
Definition of quantiles
and statement of asymptotic
distribution of sample quantiles.
- UNIT V
- Classification of Stochastic
Processes, Examples. Markov Chain
and classification of states of Markov Chain.
Suggested Readings
- Ash RB. 2000. Probability and Measure Theory.
2 Ed. Academic Press. nd
- Billingsley P. 1986. Probability and Measure.
2 Ed. John Wiley.
- Capinski M & Zastawniah. 2001. Probability
Through Problems. Springer.
- Dudewicz EJ &
Mishra SN. 1988. Modern Mathematical
Statistics. John Wiley.
- Feller W. 1972. An Introduction to Probability
Theory and its Applications. Vols. I., II. John Wiley.
- Loeve M. 1978. Probability Theory. 4 th Ed. Springer.
- Marek F. 1963.
Probability Theory and Mathematical
Statistics. John Wiley.
- Rohatgi VK & Saleh AK Md. E. 2005. An
Introduction to Probability and
- Statistics. 2 Ed. John
Wiley.
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STATISTICAL METHODS
Objective
- This course lays the
foundation of probability distributions and
sampling distributions and their application
which forms the basis of Statistical
Inference. Together with probability theory,
this course is fundamental to the discipline
of Statistics. The students are also exposed to correlation and
regression, and order statistics and
their distributions. Categorical data analysis is
also covered in this course.
Theory
- UNIT I
- Descriptive statistics:
probability distributions: Discrete
probability distributions ~ Bernoulli, Binomial, Poisson,
Negative-binomial, Geometric and Hyper Geometric,
uniform, multinomial ~ Properties of
these distributions and real life examples. Continuous
probability distributions ~ rectangular, exponential,
Cauchy, normal, gamma, beta of two
kinds, Weibull, lognormal, logistic, Pareto.
Properties of these distributions. Probability
distributions of functions of random variables.
- UNIT II
- Concepts of compound, truncated and mixture
distributions (definitions and examples). Pearsonian curves
and its various types. Sampling distributions of sample mean and
sample variance from Normal population, central and
non-central chi-Square, t and F
distributions, their properties and inter
relationships.
- UNIT III
- Concepts of random
vectors, moments and their distributions.
Bivariate Normal distribution - marginal
and conditional distributions. Distribution of
quadratic forms. Cochran theorem.
Correlation, rank correlation, correlation
ratio and intra-class correlation. Regression analysis, partial and
multiple correlation and regression.
- UNIT IV
- Sampling distribution of
correlation coefficient, regression
coefficient, correlation ratio, intra class
correlation coefficient. Categorical
data analysis - loglinear models,
Association between attributes. Variance
Stabilizing Transformations.
- UNIT V
- Order statistics,
distribution of r-th order statistics,
joint distribution of several order
statistics and their functions, marginal
distributions of order statistics, distribution of
range, median, etc.
Practical
- Fitting of discrete
distributions and test for goodness of
fit; Fitting of continuous
distributions and test for goodness of
fit; Fitting of truncated distribution;
Computation of simple, multiple and
partial correlation coefficient,
correlation ratio and
intra-class correlation; Regression
coefficients and regression equations; Fitting
of Pearsonian curves; Analysis of
association between attributes, categorical
data and log-linear models.
Suggested Readings
- Agresti A. 2002. Categorical Data Analysis.
2 Ed. John Wiley. nd
- Arnold BC, Balakrishnan
N & Nagaraja HN. 1992. A
First Course in Order Statistics. John Wiley.
- David HA & Nagaraja HN. 2003. Order
Statistics. 3 Ed. John Wiley. rd
- Dudewicz EJ &
Mishra SN. 1988. Modern Mathematical
Statistics. John Wiley.
- Huber PJ. 1981. Robust Statistics. John
Wiley.
- Johnson NL, Kotz S
& Balakrishnan N. 2000. Continuous
Univariate Distributions. John Wiley.
- Johnson NL, Kotz S
& Balakrishnan N. 2000. Discrete
Univariate Distributions. John Wiley.
- Marek F. 1963.
Probability Theory and Mathematical
Statistics. John Wiley.
- Rao CR. 1965.
Linear Statistical Inference and its
Applications. John Wiley.
- Rohatgi VK & Saleh AK Md. E. 2005. An
Introduction to Probability and
- Statistics. 2 Ed. John
Wiley.
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STATISTICAL INFERENCE
Objective
- This course lays the foundation of Statistical
Inference. The students would be taught the problems related to
point and confidence interval estimation and testing
of hypothesis. They would also be given
the concepts of nonparametric and
sequential test procedures and elements
of decision theory. Theory
- UNIT I
- Concepts of point
estimation: MSE, unbiasedness, consistency,
efficiency and sufficiency. Statement of
Neyman's Factorization theorem with
applications. MVUE, Rao-Blackwell theorem,
completeness, Lehmann- Scheffe theorem.
Fisher information, Cramer-Rao lower bound
and its applications.
- UNIT II
- Moments, minimum chi-square,
least square and maximum likelihood methods
of estimation and statements of their properties.
Interval estimation-Confidence level, CI using pivots and shortest
length CI. CI for the parameters of Normal, Exponential, Binomial
and Poisson distributions. UNIT III
- Fundamental notions of hypothesis
testing-statistical hypothesis, statistical test,
critical region, types of errors, test
function, randomized and non- randomized
tests, level of significance, power
function, most powerful tests: Neyman-Pearson
fundamental lemma, MLR families and UMP tests for
one parameter exponential
families. Concepts of
consistency, unbiasedness and invariance of tests. Likelihood
Ratio tests, statement of asymptotic properties of LR tests with
applications (including homogeneity of means and
variances).Relation between confidence interval
estimation and testing of hypothesis.
- UNIT IV
- Notions of sequential
vs fixed sample size techniques.
Wald's SPRT for testing simple null hypothesis vs
simple alternative. Termination property of SPRT,
SPRT for Binomial, Poisson, Normal and
Exponential distributions. Concepts of loss, risk and
decision functions, admissible and optimal decision
functions, estimation and testing viewed
as decision problems, conjugate families, Bayes and Minimax
decision functions with applications to estimation with quadratic
loss.
- UNIT V
- Non-parametric tests: Sign
test, Wilcoxon signed rank test, Runs
test for randomness, Kolmogorov - Smirnov
test for goodness of fit, Median test
and Wilcoxon-Mann-Whitney U-test. Chi-square
test for goodness of fit and
test for independence of attributes.
Kruskal -Wallis and Friedman's tests.
Spearman's rank correlation
and Kendall's Tau tests
for independence.
Practical
- Methods of estimation - Maximum Likelihood,
Minimum χ and Moments; 2 Confidence Interval
Estimation; MP and UMP tests; Large
Sample tests; Non-parametric tests,
Sequential Probability Ratio
Test; Decision functions.
Suggested Readings
- Box GEP & Tiao
GC. 1992. Bayesian Inference in
Statistical Analysis. John Wiley.
- Casela G & Berger
RL. 2001. Statistical Inference. Duxbury
Thompson Learning.
- Christensen R. 1990. Log Linear Models.
Springer.
- Conover WJ. 1980. Practical Nonparametric
Statistics. John Wiley.
- Dudewicz EJ &
Mishra SN. 1988. Modern Mathematical
Statistics. John Wiley.
- Gibbons JD. 1985. Non
Parametric Statistical Inference. 2 nd
Ed. Marcel Dekker.
- Kiefer JC. 1987. Introduction to Statistical
Inference. Springer.
- Lehmann EL. 1986. Testing Statistical
Hypotheses. John Wiley.
- Lehmann EL. 1986. Theory of Point Estimation.
John Wiley.
- Randles RH & Wolfe
DS. 1979. Introduction to the
Theory of Nonparametric Statistics. John Wiley.
- Rao CR. 1973. Linear
Statistical Inference and its Applications.
2 nd Ed. John Wiley.
- Rohatgi VK & Saleh AK. Md. E. 2005. An
Introduction to Probability and Statistics. 2 Ed. John
Wiley.
- Rohtagi VK. 1984. Statistical Inference. John
Wiley
- Sidney S & Castellan NJ Jr. 1988. Non
Parametric Statistical Methods for Behavioral Sciences. McGraw
Hill.
- Wald A. 2004. Sequential Analysis. Dover
Publ.
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MULTIVARIATE ANALYSIS
Objective
- This course lays the foundation of Multivariate
data analysis. Most of the data sets in
agricultural sciences are multivariate in
nature. The exposure provided to
multivariate data structure, multinomial and
multivariate normal distribution,
estimation and testing of parameters,
various data reduction methods would help the students in
having a better understanding of agricultural research data, its
presentation and analysis.
Theory
- UNIT I
- Concept of random vector, its expectation and
Variance-Covariance matrix.
- Marginal and
joint distributions.
Conditional distributions and
- Independence of random
vectors. Multinomial distribution. Multivariate
Normal distribution, marginal and conditional distributions. Sample
mean vector and its distribution. Maximum likelihood
estimates of mean vector and dispersion matrix. Tests of
hypothesis about mean vector.
- UNIT II
- Wishart distribution and
its simple properties.
- Mahalanobis D statistics.
Null distribution of Hotelling's T .
Rao's U 2 Hotelling's
T and 2 statistics and its
distribution.
- Wilks' λ criterion and statement of its
properties. Concepts of discriminant analysis, computation
of linear discriminant function,
classification between k ( ≥2)
multivariate normal populations based on
LDF and Mahalanobis D .
- UNIT III
- Principal Component
Analysis, factor analysis (simple and
multi factor models). Canonical variables and canonical
correlations. Cluster analysis, similarities and
dissimilarities, Hierarchical
clustering. Single and Complete linkage
methods.
- UNIT IV
- Path analysis and
computation of path coefficients, introduction
to multidimensional scaling, some theoretical results,
similarities, metric and non metric scaling methods. Concepts
of analysis of categorical data.
Practical
- Maximum likelihood
estimates of mean-vector and dispersion
matrix;
- Testing of hypothesis on mean vectors of
multivariate normal populations; Cluster analysis,
Discriminant function, Canonical correlation,
Principal component analysis, Factor analysis; Multivariate analysis
of variance and covariance, multidimensional scaling.
Suggested Readings
- Anderson TW. 1984. An Introduction to
Multivariate Statistical Analysis. 2 Ed. John
Wiley.
- Arnold SF. 1981. The Theory of Linear Models
and Multivariate Analysis. John Wiley.
- Giri NC. 1977. Multivariate Statistical Inference.
Academic Press.
- Johnson RA & Wichern
DW. 1988. Applied Multivariate
Statistical Analysis. Prentice Hall.
- Kshirsagar AM. 1972. Multivariate
Analysis. Marcel Dekker.
- Muirhead RJ. 1982. Aspects of Multivariate
Statistical Theory. John Wiley. nd
Ed.
- Rao CR. 1973. Linear
Statistical Inference and its Applications.
2 John Wiley.
- Rencher AC. 2002. Methods of Multivariate
Analysis. 2nd Ed. John Wiley.
- Srivastava MS &
Khatri CG. 1979. An Introduction to
Multivariate Statistics. North Holland.
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DESIGN OF EXPERIMENTS
Objective
- Design of Experiments
provides the statistical tools to get
maximum information from least amount of resources. This
course is meant to expose the students to the basic principles of
design of experiments. The students would also be
provided with a mathematical background of
various basic designs involving one-way and two
way elimination of heterogeneity and their
characterization properties. This course would
also prepare the students in deriving the
expressions for analysis of experimental data.
Theory
- UNIT I
- Elements of linear
estimation, Gauss Markoff Theorem,
relationship between BLUEs and linear zero-functions. Aitken's
transformation, test of hypothesis, analysis of variance,
partitioning of degrees of freedom.
- UNIT II
- Orthogonality, contrasts, mutually
orthogonal contrasts, analysis of
covariance; Basic principles of design
of experiments, uniformity trials, size and shape
of plots and blocks.
- UNIT III
- Basic designs - completely randomized design,
randomized complete block design and Latin
square design; orthogonal Latin squares,
mutually orthogonal Latin squares
(MOLS), Youden square designs, Graeco
Latin squares.
- UNIT IV
- Balanced incomplete block (BIB) designs -
general properties and analysis without and with recovery of intra
block information, construction of BIB designs.
Partially balanced incomplete block designs
with two associate classes - properties,
analysis and construction, Lattice
designs, alpha designs, cyclic designs,
augmented designs, general analysis of
block designs.
- UNIT V
- Factorial experiments,
confounding in symmetrical factorial experiments
(2 and 3 series), partial and
total confounding, fractional
factorials, n
n asymmetrical factorials.
- UNIT VI
- Designs for fitting
response surface; Cross-over designs.
Missing plot technique; Split plot and
Strip plot design; Groups of
experiments; Sampling in field experiments.
Practical
- Determination of size and shape of plots and
blocks from uniformity trials data; Analysis of
data generated from completely randomized
design, randomized complete block design;
Latin square design, Youden square design;
Analysis of data generated from a BIB design, lattice design, PBIB
designs; 2 , 3 factorial experiments
without and with confounding; Split n
n and strip plot designs,
repeated measurement design; Missing
plot techniques, Analysis of covariance;
Analysis of Groups of experiments, Analysis
of clinical trial experiments. Sampling in field experiments.
Suggested Readings
- Chakrabarti MC.
1962. Mathematics of Design
and Analysis of Experiments. Asia Publ.
House.
- Cochran WG & Cox DR. 1957. Experimental
Designs. 2 Ed. John Wiley. nd Dean AM & Voss D. 1999. Design and Analysis of
Experiments. Springer.
- Dey A & Mukerjee R. 1999. Fractional
Factorial Plans. John Wiley.
- Dey A 1986. Theory of Block Designs. Wiley
Eastern.
- Hall M Jr. 1986. Combinatorial Theory. John
Wiley.
- John JA &
Quenouille MH. 1977. Experiments: Design
and Analysis. Charles & Griffin.
- Kempthorne, O. 1976. Design and Analysis of
Experiments. John Wiley.
- Khuri AI & Cornell JA. 1996. Response
Surface Designs and Analysis. 2 nd
Ed. Marcel Dekker.
- Kshirsagar AM 1983. A Course in Linear
Models. Marcel Dekker.
- Montgomery DC. 2005. Design and Analysis of
Experiments. John Wiley.
- Raghavarao D. 1971. Construction and
Combinatorial Problems in Design of Experiments. John Wiley.
- Searle SR. 1971. Linear Models. John
Wiley.
- Street AP & Street
DJ. 1987. Combinatorics of Experimental
Designs. Oxford Science Publ.
- Design Resources
Server. Indian Agricultural
Statistics Research Institute(ICAR), New Delhi-110012, India.
www.iasri.res.in/design.
********************************
SAMPLING TECHNIQUES
Objective
- This course is meant
to expose the students to the techniques
of drawing representative samples from
various populations and then preparing
them on the mathematical formulations of estimating the population
parameters based on the sample data. The students would also be
exposed to the real life applications of sampling techniques and
estimation of parameters.
Theory
- UNIT I
- Sample survey vs
complete survey, probability sampling,
sample space, sampling design, sampling
strategy; Inverse sampling; Determination
of sample size; Confidence-interval; Simple random sampling,
Estimation of population proportion, Stratified
random sampling, Number of strata and
optimum points of stratification.
- UNIT II
- Ratio and regression methods of
estimation, Cluster sampling, Systematic sampling, Multistage
sampling with equal probability,
Separate and combined ratio estimator,
Double sampling, Successive sampling
-two occasions.
- UNIT III
- Non-sampling errors - sources and
classification, Non-response in surveys, Imputation
methods, Randomized response techniques,
Response errors - interpenetrating
sub-sampling.
- UNIT IV
- Sampling with varying
probabilities with and without replacement,
PPS sampling, Cumulative method and Lahiri's
method of selection, Horvitz- Thompson
estimator, Ordered and
unordered estimators, Sampling strategies
due to Midzuno-Sen and
Rao-Hartley-Cochran. Inclusion probability
proportional to size sampling, PPS
systematic sampling, Multistage sampling with unequal
probabilities, Self weighting design PPS sampling.
- UNIT V
- Unbiased ratio and
regression type estimators, Multivariate ratio
and regression type of estimators,
Design effect, Bernoulli and
Poisson sampling.
Practical
- Determination of sample
size and selection of sample; Simple
random sampling, Inverse sampling, Stratified random sampling,
Cluster sampling, systematic sampling; Ratio and
regression methods of estimation; Double
sampling, multi-stage sampling,
Imputation methods; Randomized response
techniques; Sampling with varying probabilities.
Suggested Readings
- Cassel CM, Sarndal CE & Wretman JH. 1977.
Foundations of Inference in Survey Sampling. John Wiley.
- Chaudhari A & Stenger H. 2005. Survey
Sampling Theory and Methods. 2 nd
Ed. Chapman & Hall.
- Chaudhari A & Voss JWE. 1988. Unified
Theory and Strategies of Survey Sampling. North Holland.
- Cochran WG. 1977. Sampling Techniques. John
Wiley.
- Hedayat AS & Sinha BK. 1991. Design and
Inference in Finite Population Sampling. John Wiley.
- Kish L. 1965. Survey Sampling. John
Wiley.
- Murthy MN. 1977. Sampling Theory and Methods.
2 Ed. Statistical Publ. nd Society,
Calcutta.
- Raj D & Chandhok P. 1998. Sample
Survey Theory. Narosa Publ.
- Sarndal CE, Swensson B
& Wretman J. 1992. Models
Assisted Survey Sampling. Springer.
- Sukhatme PV, Sukhatme
BV, Sukhatme S & Asok C.
1984. Sampling Theory of Surveys with
Applications. Iowa State University Press
and Indian Society of Agricultural Statistics, New Delhi. Thompson
SK. 2000. Sampling. John Wiley.
********************************
STATISTICAL GENETICS
Objective
- This course is meant to prepare the students
in applications of statistics in quantitative genetics
and breeding. The students would be
exposed to the physical basis of
inheritance, detection and estimation of
linkage, estimation of genetic parameters and development of
selection indices.
Theory
- UNIT I
- Physical basis of
inheritance. Analysis of segregation,
detection and estimation of linkage
for qualitative characters. Amount of
information about linkage, combined estimation, disturbed
segregation.
- UNIT II
- Gene and genotypic
frequencies, Random mating and Hardy
-Weinberg law, Application and
extension of the
equilibrium law, Fisher's fundamental
theorem of natural selection. Disequilibrium due to linkage for two
pairs of genes, sex-linked genes, Theory of path coefficients.
- UNIT III
- Concepts of inbreeding,
Regular system of inbreeding. Forces
affecting gene frequency - selection,
mutation and migration, equilibrium between
forces in large populations, Random
genetic drift, Effect of finite
population size.
- UNIT IV
- Polygenic system for
quantitative characters, concepts of
breeding value and dominance deviation.
Genetic variance and its partitioning,
Effect of inbreeding on quantitative
characters, Multiple allelism in
continuous variation, Sex-linked genes,
Maternal effects - estimation of
their contribution.
- UNIT V
- Correlations between relatives,
Heritability, Repeatability and Genetic correlation.
Response due to selection, Selection index and its applications
in plants and animals improvement
programmes, Correlated response to
selection. UNIT VI
- Restricted selection index.
Variance component approach and linear
regression approach for the analysis
of GE interactions. Measurement of
stability and adaptability for genotypes.
Concepts of general and specific
combining ability. Diallel and partial
diallel crosses - construction and analysis.
Practical
- Test for the single
factor segregation ratios, homogeneity of
the families with regard to single
factor segregation; Detection and estimation
of linkage parameter by different
procedures; Estimation of genotypic and
gene frequency from a given data.
Hardy-Weinberg law; Estimation of changes in gene
frequency due to systematic forces, inbreeding coefficient,
genetic components of variation,
heritability and repeatability coefficient, genetic
correlation coefficient; Examination of
effect of linkage, epistasis and
inbreeding on mean and variance of
metric traits; Mating designs; Construction
of selection index including phenotypic
index, restricted selection index. Correlated response to
selection.
Suggested Readings
- Bailey NTJ. 1961. The
Mathematical Theory of Genetic
Linkage. Clarendon Press.
- Balding DJ, Bishop M
& Cannings C. 2001. Hand Book
of Statistical Genetics. John Wiley.
- Crow JF & Kimura
M. 1970. An Introduction of Population
Genetics Theory. Harper & Row.
- Dahlberg G. 1948.
Mathematical Methods for Population
Genetics. Inter Science Publ.
- East EM & Jones DF. 1919. Inbreeding and
Outbreeding. J B Lippincott.
- Ewens WJ. 1979. Mathematics of Population
Genetics. Springer.
- Falconer DS. 1985. Introduction to
Quantitative Genetics. ELBL.
- Fisher RA. 1949. The Theory of
Inbreeding. Oliver & Boyd.
- Fisher RA. 1950.
Statistical Methods for Research Workers.
Oliver & Boyd.
- Fisher RA. 1958. The Genetical Theory of
Natural Selection. Dover Publ.
- Kempthorne O. 1957. An Introduction to Genetic
Statistics. The Iowa State Univ. Press.
- Lerner IM.
1950. Population Genetics and
Animal Improvement. Cambridge Univ.
Press.
- Lerner IM. 1954. Genetic Homeostasis. Oliver
& Boyd.
- Lerner IM. 1958. The Genetic Theory of
Selection. John Wiley.
- Li CC. 1982. Population Genetics. The
University of Chicago Press.
- Mather K & Jinks
JL. 1977. Introduction to Biometrical
Genetics. Chapman & Hall.
- Mather K & Jinks JL. 1982. Biometrical
Genetics. Chapman & Hall.
- Mather K. 1949. Biometrical Genetics.
Methuen.
- Mather K. 1951. The Measurement of Linkage
in Heredity. Methuen. Narain P. 1990. Statistical Genetics. Wiley
Eastern.
********************************
REGRESSION ANALYSIS
Objective
- This course is meant
to prepare the students in linear
and non-linear regression methods useful for statistical data
analysis. They would also be provided a
mathematical foundation behind these
techniques and their applications in agricultural
data.
Theory
- UNIT I
- Simple and Multiple
linear regressions: Least squares fit, Properties
and examples. Polynomial regression: Use of orthogonal
polynomials.
- UNIT II
- Assumptions of regression;
diagnostics and transformations; Examination
of residuals ~ Studentized residuals,
applications of residuals in detecting outliers,
identification of influential observations.
Lack of fit, Pure error. Testing
homoscedasticity and normality of errors, Durbin-Watson test. Use of
R for examining goodness of fit.
- UNIT III
- Concepts of Least
median of squares and its
applications; Concept of multicollinearity,
Analysis of multiple regression models,
estimation and testing of
regression parameters, sub-hypothesis
testing, restricted estimation.
- UNIT IV
- Weighted least squares method: Properties, and
examples. Box-Cox family of transformations. Use
of dummy variables, Selection of
variables: Forward selection,
Backward elimination. Stepwise
and Stagewise regressions.
- UNIT V
- Introduction to non-linear
models, nonlinear estimation: Least squares for
nonlinear models.
Practical
- Multiple regression fitting
with three and four independent variables;
Estimation of residuals, their applications in outlier
detection, distribution of residuals; Test
of homoscedasticity, and normality,
Box-Cox transformation; Restricted
estimation of parameters in
the model, hypothesis testing, Step wise regression
analysis; Least median of squares norm, Orthogonal polynomial
fitting.
Suggested Readings
- Barnett V & Lewis T. 1984. Outliers in
Statistical Data. John Wiley.
- Belsley DA, Kuh E
& Welsch RE. 2004. Regression
Diagnostics- Identifying Influential Data and
Sources of Collinearity. John Wiley.
- Chatterjee S, Hadi A & Price B. 1999.
Regression Analysis by Examples. John Wiley.
- Draper NR & Smith
H. 1998. Applied Regression Analysis.
3 Ed. John rd Wiley.
- McCullagh P &
Nelder JA. 1999. Generalized Linear
Models. 2 nd Ed. Chapman & Hall.
- Montgomery DC, Peck EA
& Vining GG. 2003. Introduction to
Linear
- Regression Analysis. 3 Ed. John Wiley.
rd
- Rao CR. 1973. Linear
Statistical Inference and its Applications.
2 nd Ed. John Wiley.
********************************
STATISTICAL COMPUTING
Objective
- This course is meant
for exposing the students in the
concepts of computational techniques. Various
statistical packages would be used for teaching the concepts of
computational techniques.
Theory
- UNIT I
- Introduction to statistical
packages and computing: data types
and structures, pattern recognition,
classification, association rules, graphical
methods. Data analysis principles and practice UNIT II
- ANOVA, regression and
categorical data methods; model formulation,
fitting, diagnostics and validation; Matrix
computations in linear models. Analysis of
discrete data.
- UNIT III
- Numerical linear algebra,
numerical optimization, graphical techniques,
numerical approximations, numerical
integration and Monte Carlo
methods.
- UNIT IV
- Spatial statistics; spatial
sampling; hierarchical modeling. Analysis
of cohort studies, case-control studies
and randomized clinical trials,
techniques in the analysis of survival
data and longitudinal studies, Approaches
to handling missing data, and meta-analysis.
Practical
- Data management, Graphical representation of
data, Descriptive statistics;
- General linear models ~ fitting and analysis
of residuals, outlier detection;
- Categorical data analysis, analysis of
discrete data, analysis of binary data; Numerical
algorithms; Spatial modeling, cohort
studies; Clinical trials, analysis of survival data;
Handling missing data.
Suggested Readings
- Agresti A. 2002. Categorical Data Analysis.
2 Ed. John Wiley. nd
- Everitt BS & Dunn G. 1991. Advanced
Multivariate Data Analysis. 2 Ed. nd
Arnold.
- Geisser S. 1993. Predictive Inference: An
Introduction. Chapman & Hall.
- Gelman A & Hill
J. 2006. Data Analysis Using
Regression and Multilevel/Hierarchical Models. Cambridge Univ.
Press.
- Gentle JE, Härdle W
& Mori Y. 2004. Handbook of
Computational Statistics - Concepts and Methods. Springer.
- Han J & Kamber
M. 2000. Data Mining: Concepts and Techniques.
Morgan.
- Hastie T, Tibshirani R
& Friedman R. 2001. The Elements
of Statistical Learning: Data Mining, Inference and Prediction.
Springer.
- Kennedy WJ & Gentle JE. 1980. Statistical
Computing. Marcel Dekker.
- Miller RG Jr. 1986.
Beyond ANOVA, Basics of Applied
Statistics. John Wiley.
- Rajaraman V. 1993. Computer Oriented Numerical
Methods. Prentice-Hall.
- Ross S. 2000. Introduction to Probability
Models. Academic Press.
- Ryan BF & Joiner BL. 1994. MINITAB
Handbook. 3 Ed. Duxbury Press.
- Simonoff JS. 1996. Smoothing Methods in
Statistics. Springer.
- Snell EJ. 1987. Applied
Statistics: A Handbook of BMDP
Analyses. Chapman & Hall.
- Thisted RA. 1988. Elements of Statistical
Computing. Chapman & Hall.
- Venables WN & Ripley BD. 1999. Modern
Applied Statistics With S-Plus. 3 Ed. Springer.
********************************
TIME SERIES ANALYSIS
Objective
- This course is meant
to teach the students the concepts
involved in time series data. They
would also be exposed to components
of time series, stationary models and forecasting/
projecting the future scenarios based on time series
data. It would also help them
in understanding the concepts involved in time
series data presentation, analysis and interpretation.
Theory
- UNIT I
- Components of a
time-series. Autocorrelation and Partial
autocorrelation functions, Correlogram and periodogram
analysis.
- UNIT II
- Linear stationary models: Autoregressive,
Moving average and Mixed processes. Linear
non-stationary models: Autoregressive integrated moving average
processes.
- UNIT III
- Forecasting: Minimum mean
square forecasts and their properties,
Calculating and updating forecasts.
- UNIT IV
- Model identification: Objectives, Techniques,
and Initial estimates. Model estimation: Likelihood
function, Sum of squares function,
Least squares estimates. Seasonal models.
Intervention analysis models and Outlier
detection.
Practical
- Time series analysis,
autocorrelations, correlogram and periodogram;
Linear stationary model; Linear non-stationary model; Model
identification and model estimation; Intervention analysis and
outliers detection.
- Suggested Readings
- Box GEP, Jenkins GM
& Reinsel GC. 2007. Time
Series Analysis: rd Forecasting and Control. 3 Ed. Pearson
Edu.
- Brockwell PJ & Davis
RA. 2002. Introduction to Time
Series and nd Forecasting. 2 Ed. Springer.
- Chatterjee S, Hadi A
& Price B.1999. Regression Analysis
by Examples. John
Wiley. rd
- Draper NR & Smith
H. 1998. Applied Regression Analysis.
3 Ed. John Wiley.
- Johnston J. 1984. Econometric Methods. McGraw
Hill.
- Judge GG, Hill RC,
Griffiths WE, Lutkepohl H & Lee
TC. 1988. nd Ed. Introduction
to the Theory and Practice of Econometrics.
2 John Wiley. Montgomery DC & Johnson
LA. 1976. Forecasting and Time Series Analysis.
McGraw Hill.
- Shumway RH & Stoffer
DS. 2006. Time Series Analysis
and its Applications: With R Examples. 2 Ed.
Springer.
********************************
ACTUARIAL STATISTICS
Objective
- This course is meant to expose to the students
to the statistical techniques such as probability
models, life tables, insurance and
annuities. The students would also
be exposed top practical applications
of these techniques in computation
of premiums that include expenses,
general expenses, types of expenses and per policy
expenses.
Theory
- UNIT
I
- Insurance and utility
theory, models for individual claims and their
sums, survival function, curtate future lifetime, force of
mortality. UNIT II
- Life table and its relation with survival
function, examples, assumptions for fractional ages,
some analytical laws of mortality,
select and ultimate tables.
- UNIT III
- Multiple life functions,
joint life and last survivor status,
insurance and annuity benefits through
multiple life functions evaluation for special
mortality laws. Multiple decrement models,
deterministic and random survivorship
groups, associated single decrement tables,
central rates of multiple decrement, net single premiums
and their numerical evaluations.
- UNIT IV
- Distribution of aggregate
claims, compound Poisson distribution and
its applications.
- UNIT V
- Principles of compound interest: Nominal and
effective rates of interest and discount, force of
interest and discount, compound interest,
accumulation factor, continuous compounding.
- UNIT VI
- Insurance payable at
the moment of death and at the
end of the year of death-level benefit
insurance, endowment insurance, deferred insurance and varying
benefit insurance, recursions, commutation functions.
- UNIT VII
- Life annuities: Single
payment, continuous life annuities, discrete
life annuities, life annuities with
monthly payments, commutation functions, varying
annuities, recursions, complete
annuities-immediate and apportionable
annuities-due.
- UNIT VIII
- Net premiums: Continuous
and discrete premiums, true monthly
payment premiums, apportionable premiums, commutation functions,
accumulation type benefits. Payment
premiums, apportionable premiums, commutation
functions, accumulation type benefits. Net
premium reserves: Continuous and discrete
net premium reserve, reserves on a
semi-continuous basis, reserves based on true monthly
premiums, reserves on an apportionable or discounted continuous
basis, reserves at fractional durations, allocations of loss
to policy years, recursive formulas
and differential equations for reserves,
commutation functions.
- UNIT IX
- Some practical
considerations: Premiums that include
expenses-general expenses types of
expenses, per policy
expenses. Claim amount distributions,
approximating the individual model, stop-loss insurance.
Suggested Readings
- Atkinson ME & Dickson DCM. 2000. An
Introduction to Actuarial Studies. Elgar Publ.
- Bedford T & Cooke R. 2001. Probabilistic
Risk Analysis. Cambridge.
- Booth PM, Chadburn RG,
Cooper DR, Haberman S & James
DE. 1999.
- Modern Actuarial Theory and Practice. Chapman
& Hall.
- Borowiak Dale
S. 2003. Financial and
Actuarial Statistics: An Introduction. 2003.
Marcel Dekker.
- Bowers NL, Gerber HU,
Hickman JC, Jones DA & Nesbitt
CJ. 1997. nd Actuarial Mathematics. 2 Ed. Society
of Actuaries, Ithaca, Illinois.
- Daykin CD, Pentikainen T & Pesonen M.
1994. Practical Risk Theory for Actuaries. Chapman & Hall.
- Klugman SA, Panjer HH,
Willmotand GE & Venter GG. 1998.
Loss Models: From data to Decisions. John Wiley.
- Medina PK & Merino S. 2003. Mathematical
Finance and Probability: A Discrete Introduction. Basel,
Birkhauser.
- Neill A. 1977. Life Contingencies.
Butterworth-Heinemann.
- Rolski T, Schmidli H, Schmidt V & Teugels
J. 1998. Stochastic Processes for Insurance and Finance. John
Wiley.
- Rotar VI. 2006. Actuarial
Models. The Mathematics of
Insurance. Chapman & Hall/CRC.
- Spurgeon ET. 1972. Life Contingencies.
Cambridge Univ. Press.
********************************
BIOINFORMATICS
Objective
- Bioinformatics is a
new emerging area. It is an
integration of Statistics, Computer applications and
Biology. The trained manpower in the area of
Bioinformatics is required for meeting the new challenges in teaching
and research in the discipline of Agricultural Sciences. This course
is meant to train the students on
concepts of basic biology, statistical
techniques and computational techniques for understanding
bioinformatics principals.
Theory
- UNIT I
- Basic Biology: Cell, genes, gene structures,
gene expression and regulation, Molecular tools, nucleotides,
nucleic acids, markers, proteins and enzymes, bioenergetics,
single nucleotide polymorphism, expressed sequence
tag. Structural and functional genomics: Organization and structure
of genomes, genome mapping, assembling of
physical maps, strategies and techniques for
genome sequencing and analysis.
- UNIT II
- Computing techniques: OS
and Programming Languages - Linux,
perl, bioperl, cgi, MySQL, phpMyAdmin;
Coding for browsing biological databases
on web, parsing & annotation of
genomic sequences; Database designing; Computer networks
- Internet, World wide web, Web browsers - EMBnet, NCBI; Databases
on public domain pertaining to Nucleic acid sequences,
protein sequences, SNPs, etc.; Searching
sequence databases, Structural databases.
- UNIT III
- Statistical Techniques: MANOVA, Cluster
analysis, Discriminant analysis,
- Principal component
analysis, Principal
coordinate analysis, Multidimensional
scaling; Multiple regression
analysis; Likelihood approach in estimation and
testing; Resampling techniques - Bootstrapping and Jack-knifing;
Hidden Markov Models; Bayesian estimation and Gibbs
sampling;
- UNIT IV
- Tools for Bioinformatics:
DNA Sequence Analysis - Features of
DNA sequence analysis, Approaches to EST
analysis; Pairwise alignment techniques:
Comparing two sequences, PAM and
BLOSUM, Global alignment (The Needleman and Wunsch
algorithm), Local Alignment (The Smith-Waterman
algorithm), Dynamic programming, Pairwise
database searching; Sequence analysis- BLAST
and other related tools, Multiple alignment
and database search using motif models,
ClustalW, Phylogeny; Databases on SNPs; EM algorithm and other
methods to discover common motifs in biosequences;
Gene prediction based on Neural
Networks, Genetic algorithms, Hidden Markov
models. Computational analysis of protein
sequence, structure and function; Design
and Analysis of microarray
experiments.
Suggested Readings
- Baldi P & Brunak
S. 2001. Bioinformatics: The Machine
Learning nd Approach. 2 Ed. (Adaptive Computation and
Machine Learning). MIT Press.
- Baxevanis AD &
Francis BF. (Eds.). 2004. Bioinformatics:
A Practical Guide to the Analysis of Genes and Proteins. John
Wiley.
- Bergeron BP. 2002. Bioinformatics Computing.
Prentice Hall.
- Duda RO, Hart PE & Stork DG. 1999. Pattern
Classification. John Wiley.
- Ewens WJ & Grant
GR. 2001. Statistical Methods in
Bioinformatics: An Introduction (Statistics for Biology and Health).
Springer.
- Hunt S & Livesy F. (Eds.). 2000.
Functional Genomics: A Practical Approach (The Practical Approach Series,
235). Oxford Univ. Press.
- Jones NC & Pevzner
PA. 2004. An Introduction to
Bioinformatics Algorithims. MIT Press.
- Koski T & Koskinen T. 2001. Hidden Markov
Models for Bioinformatics. Kluwer.
- Krane DE & Raymer ML. 2002. Fundamental
Concepts of Bio-informatics. Benjamin / Cummings.
- Krawetz SA &
Womble DD. 2003. Introduction to
Bioinformatics: A Theoretical and Practical Approach. Humana
Press.
- Lesk AM. 2002. Introduction to
Bio-informatics. Oxford Univ. Press.
- Percus JK. 2001.
Mathematics of Genome Analysis. Cambridge
Univ. Press.
- Sorensen D & Gianola
D. 2002. Likelihood, Bayesian and
MCMC Methods in Genetics. Springer.
- Tisdall JD. 2001.
Mastering Perl for Bioinformatics. O'Reilly
& Associates.
- Tisdall JD. 2003.
Beginning Perl for Bioinformatics. O'Reilly
& Associates.
- Wang JTL, Zaki MJ,
Toivonen HTT & Shasha D. 2004.
Data Mining in Bioinformatics. Springer.
- Wu CH & McLarty JW. 2000. Neural Networks
and Genome Informatics. Elsevier.
- Wunschiers R. 2004. Computational Biology
Unix/Linux, Data Processing and Programming. Springer.
********************************
ECONOMETRICS
Objective
- This course is meant for training the students
in econometric methods and their applications in agriculture. This
course would enable the students in understanding the
economic phenomena through statistical tools
and economics principles.
- Theory
- UNIT I
- Representation of Economic
phenomenon, relationship among economic
variables, linear and non linear economic models,
single equation general linear regression model, basic assumptions,
Ordinary least squares method of estimation for simple and multiple
regression models; summary statistics correlation matrix,
co-efficient of multiple determination, standard errors of estimated
parameters, tests of significance and
confidence interval estimation. BLUE properties of
Least Squares estimates. Chow test, test of improvement
of fit through additional regressors.
Maximum likelihood estimation.
- UNIT II
- Heteroscedasticity, Auto-correlation, Durbin
Watson test, Multicollinearity.
- Stochastic regressors,
- Errors in variables,
Use of instrumental variables in
regression analysis. Dummy Variables.
Distributed Lag models: Koyck's Geometric
Lag scheme, Adaptive Expectation and
Partial Adjustment Mode, Rational Expectation
Models and test for rationality.
- UNIT III
- Simultaneous equation
model: Basic rationale,
Consequences of simultaneous relations, Identification
problem, Conditions of Identification, Indirect Least
Squares, Two-stage least squares, K-class
estimators,
- Limited Information and Full Information
Maximum Likelihood Methods,
- Three stage least squares,
Generalized least squares, Recursive models,
SURE Models. Mixed Estimation Methods, use of instrumental
variables, pooling of cross-section and
time series data, Principal Component
Methods.
- UNIT IV
- Problem and Construction of index numbers and
their tests; fixed and chain based index numbers; Construction of
cost of living index number.
- UNIT V
- Demand analysis - Demand and Supply Curves;
Determination of demand curves from market
data. Engel's Law and the Engel's
Curves, Income distribution and method of
its estimation, Pareto's Curve, Income
inequality measures.
Suggested Readings
- Croxton FE & Cowden DJ. 1979. Applied
General Statistics. Prentice Hall of India.
- Johnston J. 1984. Econometric Methods. McGraw
Hill.
- Judge GC, Hill RC,
Griffiths WE, Lutkepohl H & Lee
TC. 1988. nd
- Ed. Introduction to the
Theory and Practice of Econometrics. 2 John
Wiley.
- Kmenta J. 1986. Elements of Econometrics.
2 Ed. University of Michigan nd
Press.
- Koop G. 2007. Introduction to Econometrics.
John Wiley. rd
- Maddala GS. 2001. Introduction to
Econometrics. 3 Ed. John Wiley.
- Pindyck RS &
Rubinfeld DL. 1998. Econometric Models
and Economic Forecasts. 4 Ed. McGraw Hill. th rd
- Verbeek M. 2008. A Guide to Modern
Econometrics. 3 Ed. John Wiley.
********************************
STATISTICAL QUALITY CONTROL
Objective
- This course is meant
for exposing the students to the
concepts of Statistical Quality Control and their
applications in agribusiness and agro- processing
industries. This course would enable
the students to have an idea about the
statistical techniques used in quality control. students who do not
have sufficient background of Statistical Methods.
Theory
- UNIT I
- Introduction to Statistical
Quality Control; Control Charts for Variables - Mean,
Standard deviation and Range charts;
Statistical basis; Rational subgroups.
- UNIT II
- Control charts for attributes- 'np', 'p' and
'c' charts. UNIT III
- Fundamental concepts of
acceptance, sampling plans, single, double
and sequential sampling plans for attributes inspection.
- UNIT IV
- Sampling inspection tables
for selection of single and double
sampling plans.
Suggested Readings
- Cowden DJ. 1957. Statistical Methods in
Quality Control. Prentice Hall of India.
- Dodge HF & Romig HG. 1959. Sampling
Inspection Tables. John Wiley.
- Duncan A.J. 1986. Quality Control and
Industrial Statistics. 5th Ed. Irwin Book Co.
- Grant EL &
Leavenworth RS. 1996. Statistical Quality
Control. 7 Ed. th McGraw Hill.
- Montgomery DC. 2005. Introduction to
Statistical Quality Control. 5 Ed. th John Wiley.
- Wetherill G.B. 1977.
Sampling Inspection and Quality Control.
Halsted Press.
********************************
OPTIMIZATION TECHNIQUES
Objective
- This course is meant for exposing the students
to the mathematical details of the techniques
for obtaining optimum solutions under
constraints for desired output. They will
be taught numerical methods of
optimization, linear programming techniques,
non-linear programming and multiple objective
programming. Students will also be
exposed to practical applications of these
techniques.
Theory
- UNIT
I
- Classical Optimization
Techniques: Necessary Conditions
for an
- Extremum. Constrained
Optimization: Lagrange Multipliers, Statistical
Applications. Optimization and
Inequalities. Classical Inequalities, like
Cauchy-Schwarz Inequality, Jensen Inequality and Markov Inequality.
- UNIT II
- Numerical Methods of
Optimization: Numerical Evaluation of Roots
of Equations, Direct Search Methods, Sequential Search Methods --
Fibonacci
- Search Method. Random Search Method -
Method of Hooke and Jeeves,
- Simplex Search Method.
Gradient Methods, like Newton's Method,
and
- Method of Steepest
Ascent. Nonlinear Regression and
Other Statistical Algorithms, like Expectation - Maximization
Algorithm.
- UNIT III
- Linear programming
Techniques - Simplex Method,
Karmarkar's
- Algorithm, Duality and Sensitivity Analysis.
Zero-sum Two-person Finite Games and Linear
Programming. Integer Programming. Statistical
Applications.
- UNIT IV
- Nonlinear Programming and
its Examples. Kuhn-Tucker
Conditions.
- Quadratic Programming.
Convex Programming. Basics
of Stochastic
- Programming. Applications. Elements
of Multiple Objective
- Programming. Dynamic Programming,
Optimal Control Theory - Pontryagin's
Maximum Principle, Time-Optimal Control Problems.
Practical
- Problems based on
classical optimization techniques; Problems
based on optimization techniques with
constraints; Minimization problems using numerical
methods; Linear programming (LP) problems through graphical
method; LP problem by Simplex method;
LP problem using simplex method
(Two-phase method); LP problem using primal
and dual method; Sensitivity analysis for
LP problem; LP problem using
Karmarkar's method; Problems based on
Quadratic programming; Problems based on
Integer programming; Problems
based on Dynamic programming;
Problems based on Pontryagin's Maximum Principle.
Suggested Readings
- Rao SS. 2007.
Engineering Optimization: Theory and
Practice. 3 rd Ed. New Age.
- Rustagi JS. 1994. Optimization Techniques in
Statistics. Academic Press.
- Taha HA. 2007.
Operations Research: Introduction with CD. 8
Pearson Edu.
- Zeleny M. 1974. Linear Multiobjective
Programming. Springer.
********************************
DEMOGRAPHY
Objective
- This course is meant for training the students
in measures of demographic indices, estimation
procedures of demographic parameters.
Students would also be exposed to population projection techniques
and principles involved in bioassays.
Theory
- UNIT I
- Introduction to vital statistics, crude and
standard mortality and morbidity rates, Estimation
of mortality, Measures of fertility
and mortality, period and cohort measures.
- UNIT II
- Life tables and their applications, methods of
construction of abridged life tables, Increment-Decrement Life
Tables.
- UNIT III
- Stationary and stable populations, Migration
and immigration. Application of stable population
theory to estimate vital rates,
migration and its estimation. Demographic relations in
Nonstable populations. Measurement of population growth,
Lotka's model(deterministic) and intrinsic
rate of growth, Measures of mortality and morbidity, Period
and
- UNIT IV
- Principle of biological assays, parallel line
and slope ratio assays, choice of doses and efficiency
in assays quantal responses, probit
and logit transformations, epidemiological
models.
Suggested Readings
- Cox DR. 1957. Demography. Cambridge
Univ. Press.
- Finney DJ. 1981. Statistical Methods in
Biological Assays. Charles Griffin.
- Fleiss JL. 1981. Statistical Methods for Rates
and Proportions. John Wiley.
- Lawless JF. 1982. Statistical Models and
Methods for Lifetime Data. John Wiley.
- MacMahon B & Pugh
TF. 1970. Epidemiology- Principles and
Methods. Little Brown, Boston.
- Mann NR, Schafer RE & Singpurwalla ND.
1974. Methods for Statistical Analysis of Reliability and Life Data. John
Wiley.
- Newell C. 1988. Methods and Models in
Demography. Guilford Publ.
- Preston S, Heuveline P & Guillot M. 2001.
Demography: Measuring and Modeling Population Processes. Blackwell
Publ.
- Rowland DT. 2004. Demographic Methods and
Concepts. Oxford Press.
- Siegel JS & Swanson
DA. 2004. The Methods and
Material of Demography. 2 Ed. Elsevier.
- Woolson FR. 1987.
Statistical Methods for the Analysis
of Biomedical Data. John Wiley.
********************************
STATISTICAL METHODS FOR LIFE SCIENCES
Objective
- This course focuses on
statistical methods for discrete data
collected in public health, clinical
and biological studies including survival
analysis. This would enable the
students to understand the principles
of different statistical techniques useful in public health
and clinical studies conducted.
Theory
- UNIT I
- Proportions and counts, contingency tables,
logistic regression models, Poisson regression and log-linear
models, models for polytomous data and generalized linear
models.
- UNIT II
- Computing techniques,
numerical methods, simulation
and general implementation of biostatistical
analysis techniques with emphasis on data applications.
Analysis of survival time data using
parametric and non- parametric models, hypothesis testing,
and methods for analyzing censored (partially observed)
data with covariates. Topics include
marginal estimation of a survival
function, estimation of a generalized
multivariate linear regression model (allowing missing covariates
and/or outcomes).
- UNIT III
- Proportional Hazard model: Methods of
estimation, estimation of survival functions, time-dependent
covariates, estimation of a
multiplicative intensity model (such as Cox proportional hazards
model) and estimation of causal parameters assuming marginal
structural models.
- UNIT IV
- General theory for developing locally
efficient estimators of the parameters of interest in
censored data models. Rank tests
with censored data. Computing techniques,
numerical methods, simulation
and general implementation of biostatistical
analysis techniques with emphasis on data applications.
- UNIT V
- Newton, scoring, and EM
algorithms for maximization; smoothing
methods; bootstrapping; trees and neural
networks; clustering; isotonic regression; Markov chain
Monte Carlo methods.
Suggested Readings
- Biswas S. 1995. Applied
Stochastic Processes. A Biostatistical and
Population Oriented Approach. Wiley Eastern Ltd.
- Collett D. 2003. Modeling Survival Data in
Medical Research. Chapman & Hall.
- Cox DR & Oakes D. 1984. Analysis of
Survival Data. Chapman & Hall.
- Hosmer DW Jr. &
Lemeshow S. 1999. Applied Survival
Analysis: Regression Modeling or Time to Event. John
Wiley.
- Klein JP &
Moeschberger ML. 2003. Survival Analysis:
Techniques for Censored and Truncated Data. Springer.
- Kleinbaum DG & Klein M 2005. Survival
Analysis. A Self Learning Text. Springer.
- Kleinbaum DG & Klein M. 2005. Logistic
Regression. 2nd Ed. Springer.
- Lee ET. 1992. Statistical Methods for Survival
Data Analysis. John Wiley. Miller RG. 1981. Survival Analysis. John
Wiley.
- Therneau TM & Grambsch PM. 2000. Modeling
Survival Data: Extending the Cox Model. Springer.
********************************
STATISTICAL ECOLOGY
Objective
- This course is meant for exposing the students
to the importance and use of statistical methods
in collections of ecological data,
species-abundance relations, community classification and community
interpretation.
Theory
- UNIT I
- Ecological data,
Ecological sampling;
Spatial pattern analysis: Distribution
methods, Quadrant-variance methods, Distance methods.
- UNIT II
- Species-abundance relations:
Distribution models, Diversity
indices; Species affinity: Niche-overlap
indices, interspecific association,
interspecific covariation.
- UNIT III
- Community classification:
Resemblance functions, Association analysis,
Cluster analysis; Community Ordination: Polar
Ordination, Principal Component Analysis, Correspondence
analysis, Nonlinear ordination.
- UNIT IV
- Community interpretation:
Classification Interpretation and Ordination
Interpretation.
Suggested Readings
- Pielou EC. 1970. An introduction to
Mathematical Ecology. John Wiley.
- Reynolds JF & Ludwig
JA. 1988. Statistical Ecology: A
Primer on Methods and Computing. John Wiley.
- Young LJ, Young JH & Young J. 1998.
Statistical Ecology: A Population Perspective. Kluwer.
********************************
ADVANCED STATISTICAL COMPUTING
Objective
- This is an advanced course in Statistical
Computing that aims at describing some advanced
level topics in this area of
research with a very strong potential of
applications. This course also prepares students for undertaking
research in this area. This also
helps prepare students for applications
of this important subject to
agricultural sciences and use of
statistical packages.
Theory
- UNIT I
- Measures of association. Structural models for
discrete data in two or more dimensions.
- Estimation in complete
tables. Goodness of fit, choice of
a model. Generalized Linear Model
for discrete data, Poisson and
Logistic regression models. Log-linear models.
- UNIT II
- Elements of inference
for cross-classification tables. Models for
nominal and ordinal response.
- UNIT III
- Computational problems and
techniques for robust linear
regression, nonlinear and generalized linear
regression problem, tree-structured regression
and classification, cluster analysis,
smoothing and function estimation, robust multivariate
analysis.
- UNIT IV
- Analysis of
incomplete data: EM
algorithm, single and
multiple imputations. Markov Chain, Monte Carlo and annealing
techniques, Neural Networks, Association Rules and learning
algorithms.
- UNIT V
- Linear mixed effects models, generalized
linear models for correlated data (including generalized
estimating equations), computational issues
and methods for fitting models, and dropout or other missing
data.
- UNIT VI
- Multivariate tests of
linear hypotheses, multiple comparisons,
confidence regions, prediction
intervals, statistical power,
transformations and diagnostics, growth curve models,
dose-response models.
Practical
- Analysis of qualitative
data; Generalized linear for correlated
data; Generalized linear models for discrete data; Robust methods of
estimation and testing of non-normal data;
Robust multivariate analysis; Cluster
analysis; Analysis of Incomplete data;
Classification and prediction using artificial
neural networks; Markov Chain; Analysis of data having random
effects using Linear mixed effects
models; Analysis of data with missing
observations; Applications of multiple
comparison procedures; Building Simultaneous
confidence intervals; Fitting of growth
curve models to growth data; Fitting of dose-response
curves and estimation of parameters.
Suggested Readings
- Everitt BS & Dunn G. 1991. Advanced
Multivariate Data Analysis. 2 Ed. nd
Arnold.
- Geisser S. 1993. Predictive Inference: An
Introduction. Chapman & Hall.
- Gentle JE, Härdle W
& Mori Y. 2004. Handbook of
Computational Statistics -Concepts and Methods. Springer.
- Han J & Kamber M. 2000. Data Mining:
Concepts and Techniques. Morgan.
- Hastie T, Tibshirani R
& Friedman R. 2001. The Elements
of Statistical Learning: Data Mining, Inference and Prediction.
Springer.
- Kennedy WJ & Gentle JE. 1980. Statistical
Computing. Marcel Dekker.
- Miller RG Jr. 1986.
Beyond ANOVA, Basics of Applied
Statistics. John Wiley.
- Rajaraman V. 1993. Computer Oriented Numerical
Methods. Prentice-Hall.
- Robert CP &
Casella G. 2004. Monte Carlo
Statistical Methods. 2 Springer.
- Ross S. 2000. Introduction to Probability
Models. Academic Press.
- Simonoff JS. 1996. Smoothing Methods in
Statistics. Springer.
- Thisted RA. 1988. Elements of Statistical
Computing. Chapman & Hall.
- Venables WN & Ripley BD. 1999. Modern
Applied Statistics With S-Plus. 3 Ed. Springer.
- Free Statistical Softwares: http://freestatistics.altervista.org/en/stat.php.
- Design Resources Server:
www.iasri.res.in.
- SAS Online Doc 9.1.3:
http://support.sas.com/onlinedoc/913/docMainpage.jsp
********************************
SIMULATION TECHNIQUES
Objective
- This course is meant for students who have a
good knowledge in Statistical Inference and Statistical
Computing. This course would prepare students
for undertaking research in the area of
simulation techniques and their applications to agricultural
sciences.
Theory
- UNIT I
- Review of simulation methods; Implementation
of simulation methods - for various probability
models, and resampling
methods: theory and application of the
jackknife and the bootstrap.
- UNIT II
- Randomization tests,
analysis using computer
software packages. Simulating multivariate
distributions, MCMC methods and Gibbs sampler.
- UNIT III
- Correlograms, periodograms, fast Fourier
transforms, power spectra, cross- spectra, coherences, ARMA and
transfer-function models, spectral-domain regression.
Simulated data sets to be analyzed
using popular computer software packages
- UNIT IV
- Stochastic simulation: Markov
Chain, Monte Carlo, Gibbs'
sampling, Hastings-Metropolis algorithms, critical
slowing-down and remedies, auxiliary
variables, simulated tempering, reversible-
jump MCMC and multi-grid methods.
Practical
- Simulation from
various probability models;
Resampling methods, jackknife and the
bootstrap; Randomization tests; Simulating
multivariate distributions, MCMC methods
and Gibbs sampler;
Correlograms, periodograms, fast Fourier transforms,
power spectra, cross-spectra, coherences;
ARMA and transfer-function
models, spectral-domain regression; Simulated
data sets to be analyzed using
popular computer software packages; Markov
Chain, Monte Carlo, Gibbs' sampling;
Reversible- jump MCMC and multi-grid methods.
Suggested Readings
- Averill ML, Kelton D.
2005. Simulation, Modeling and Analysis.
Tata McGraw Hill.
- Balakrishnan N, Melas
VB & Ermakov S. (Ed.). 2000.
Advances in Stochastic Simulation Methods. Basel-Birkhauser.
- Banks J. (Ed.). 1998.
Handbook of Simulation: Principles, Methodology,
Advances, Applications and Practice. John Wiley.
- Brately P, Fox BL & Scharge LE. 1987. A
Guide to Simulation. Springer.
- Davison AC & Hinkley
DV. 2003. Bootstrap Methods and
their Application. Cambridge Univ. Press.
- Gamerman D, Lopes HF & Lopes HF.
2006. Markov Chain Monte Carlo:
- Stochastic Simulation for Bayesian Inference.
CRC Press.
- Gardner FM & Baker JD. 1997.
Simulation Techniques Set. John Wiley.
- Gentle JE. 2005. Random Number Generation and
Monte Carlo Methods. Springer.
- Janacek G & Louise
S. 1993. Time Series: Forecasting,
Simulation, Applications. Ellis Horwood Series
in Mathematics and Its Applications.
- Kleijnen J & Groenendaal WV. 1992.
Simulation: A Statistical Perspective. John Wiley.
- Kleijnen J. 1974 (Part
I), 1975 (Part II). Statistical
Techniques in Simulation. Marcel Dekker.
- Law A & Kelton
D. 2000. Simulation Modeling and
Analysis. McGraw Hill.
- Press WH, Flannery BP, Tenkolsky SA &
Vetterling WT. 1986. Numerical Recipes. Cambridge Univ. Press.
- Ripley BD. 1987. Stochastic Simulation. John
Wiley. Ross SM. 1997. Simulation. John Wiley.
********************************
ADVANCED STATISTICAL METHODS
Objective
- This is an advanced
course in Statistical Methods that
aims at describing some advanced level
topics in this area of research
with a very strong potential of applications. This
course also prepares students for undertaking research in
this area. This also helps prepare
students for applications of this important
subject to agricultural sciences.
Theory
- UNIT I
- Ridge regression: Basic
form, Use as a selection procedure.
Robust regression: Least absolute
deviations regression, M-estimators, Least median
of squares regression. Nonparametric regression.
- UNIT II
- Introduction to the
theory and applications of generalized
linear models, fixed effects, random
effects and mixed effects models,
estimation of variance components from
unbalanced data. Unified theory of
least - squares, MINQUE, MIVQUE, REML. UNIT III
- Quasi-likelihoods, and
generalized estimating equations
- logistic regression,
over-dispersion, Poisson regression,
log-linear models, conditional likelihoods,
generalized mixed models,
and regression diagnostics. Theory of statistical
methods for analyzing categorical data by means of
linear models; multifactor and multi-response
situations; interpretation of interactions.
- UNIT IV
- Fitting of a generalized
linear model, mixed model and
variance components estimation, MINQUE, MIVQUE, REML.
- UNIT V
- Fitting of Logistic regression, Poisson
regression, ridge regression, robust regression, non-parametric
regression.
Suggested Readings
- Chatterjee S, Hadi A
& Price B.1999. Regression Analysis
by Examples. John Wiley.
- Draper NR & Smith
H. 1998. Applied Regression Analysis.
3 Ed. John rd Wiley.
- Rao CR. 1965. Linear Statistical
Inference and its Applications. 2 nd
Ed. John Wiley.
- Searle SR, Casella G & McCulloch CE. 1992.
Variance Components. John Wiley.
- Searle SR. 1971. Linear Models. John
Wiley.
********************************
ADVANCED STATISTICAL INFERENCE
Objective
- This course aims at
describing the advanced level topics
in statistical methods and statistical
inference. This course would prepare students
to have a strong base in basic
statistics that would help them in
undertake basic and applied research in Statistics.
Theory
- UNIT I
- Robust estimation and robust
tests, Robustness, M-estimates. L-estimates, asymptotic
techniques, Bayesian inference. Detection
and handling of outliers in statistical
data.
- UNIT II
- Loglinear models, saturated models,
hierarchical models, Analysis of multi - dimensional
contingency tables. Non-parametric maximum
likelihood estimation.
- UNIT III
- Density Estimation:
Density Estimation in
the Exploration and
- Presentation of Data. Survey of
existing methods. The Kernel method for
- Univariate Data: Rosenblatts
naïve estimator, its bias and
variance.
- Consistency of general
Kernel estimators, MSE and IMSE.
Asymptotic
- normality of Kernel
estimates of density. Estimation of
distribution by method of kernels.
- UNIT IV
- Consistency and asymptotic
normality (CAN) of real
and vector parameters. Invariance of
consistency under continuous transformation.
Invariance of CAN estimators under
differentiable transformations, generation of
CAN estimators using central limit
theorem. Exponential class of densities
and multinomial distribution, Cramer-Huzurbazar
theorem, method of scoring.
- UNIT V
- Efficiency: asymptotic relative efficiency and
Pitman's theorem. Concepts and examples of Bahadur efficiency and
Hodges-Lehmanns efficiency with examples. The
concepts of Rao's second order
efficiency and Hodges- Lehmann's Deficiency
with examples. Rank tests,
permutation tests, asymptotic theory of rank
tests under null and alternative
(contiguous) hypotheses.
- UNIT VI
- Inference on Markov Chains: Maximum
likelihood estimation and testing of Transition Probability Matrix
of a Markov Chain, testing for order of a Markov chain, estimation
of functions of transition probabilities.
- UNIT VII
- Concept of loss, risk
and decision functions, admissible and
optimal decision functions, a-priori and posteriori distributions,
conjugate families. Bayes and Minimax decision
rules and some basic results on
them.
- Estimation and testing
viewed as cases of decision problems.
Bayes and Minimax decision functions with applications to
estimation with quadratic loss function. Concept
of Bayesian sequential analysis. Bayes
sequential decision rule. The SPRT as
a Bayes procedure. Minimax sequential procedure.
- UNIT VIII
- U-Statistics: definitions
of estimable parametric
function, kernel, symmetric kernel and U-statistics.
Variance and covariance of U-statistics. Hoeffding's decomposition
of U-statistics -examples. U-statistics based on sampling from
finite populations and weighted U-statistics with examples.
Some convergence results on U-statistics.
Asymptotic normality of U- statistics with
examples.
- UNIT IX
- Resampling Plans :
Estimation of standard and biased deviation
of point estimator by the Jackknife,
the Bootstrap, the Infinitesimal Jackknife,
the Delta and the Influence function
methods. Estimation of excess error in
regression by cross validation, the
Jackknife and Bootstrap methods. Nonparametric
confidence interval for the median
by the Percentile method.
Suggested Readings
- Casela G & Berger
RL. 2001. Statistical Inference. Duxbury
Thompson Learning.
- Daniel W.1990. Applied Nonparametric
Statistics. Houghton
Mifflin, Boston.
- DeGroot MH. 1970. Optimal Statistical
Decisions. McGraw Hill.
- Efron B &
Tibshirani RJ. 1993. An Introduction
to Bootstrap. Chapman Hall/CRC.
- Ferguson TS. 1967. Mathematical Statistics, A Decision
Theoretic Approach. Academic Press.
- Gibbons JD & Chakraborty S. 1992.
Non-parametric Statistical Inference. Marcel Dekker.
- Gray HL & Schucany
WR.1972. The Generalized Jackknife
Statistics. Marcel Dekker.
- Kale BK.1999. A First Course on Parametric
Inference. Narosa Publ.
- Prakasa Rao BLS. 1983. Nonparametric
Functional Estimation. Academic Press.
- Rao CR.1965. Linear Statistical Inference and
its Applications. 2 Ed. nd John
Wiley.
- Silverman BW. 1986. Density Estimation for
Statistics and Data Analysis.
- Chapman & Hall.
- Silvey SD. 1975. Statistical Inference.
Chapman & Hall.
- Tapia RA &
Thompson JR. 1978. Nonparametric Probability
Density Estimation. Johns Hopkins Univ. Press.
- Tiku ML, TanWY &
Balakrishnan N. 1986. Robust Inference.
Marcel Dekker.
- Wald A. 2004. Sequential Analysis. Dover
Publ.
- Wasserman L. 2006. All of Nonparametric
Statistics. Springer.
********************************
ADVANCED DESIGN OF EXPERIMENTS
Objective
- This is an advanced
course in Design of Experiments
that aims at describing some
advanced level topics for students who
wish to pursue research in Design
of Experiments. This course prepares
students for undertaking research in
this area. This also helps prepare
students for applications of this important subject to
agricultural sciences.
Theory
- UNIT I
- General properties and
analysis of block designs. Balancing criteria.
m- associate PBIB designs, and their
association schemes including lattice designs -
properties and construction, Designs for test treatment - control(s)
comparisons; Nested block designs, Mating designs. UNIT II
- General properties and analysis of two-way
heterogeneity designs, Youden type designs,
generalized Youden designs, Pseudo Youden
designs. Structurally Incomplete block designs, Designs for
two sets of treatments.
- UNIT III
- Balanced factorial experiments - characterization
and analysis (symmetrical and asymmetrical factorials). Factorial
experiments with extra treatment(s). Orthogonal arrays,
Mixed orthogonal arrays, balanced arrays,
Fractional replication, Regular and irregular fractions.
- UNIT IV
- Response surface designs
- Symmetrical and asymmetrical
factorials, Response optimization and slope estimation, Blocking.
Canonical analysis and ridge analysis.
Experiments with mixtures: design and
analysis. Experiments with qualitative cum quantitative
factors.
- UNIT V
- Optimality criteria and optimality of designs,
robustness of designs against loss of data, outliers, etc.
Diagnostics in design of experiments.
Suggested Readings
- Chakraborti MC.
1962. Mathematics of Design
and Analysis of Experiments. Asia Publ.
House.
- Dean AM & Voss D. 1999. Design and
Analysis of Experiments. Springer.
- Dey A & Mukerjee R. 1999. Fractional
Factorial Plans. John Wiley.
- Dey A 1986. Theory of Block Designs. Wiley
Eastern.
- Hall M Jr. 1986. Combinatorial Theory. John
Wiley.
- Hedayat AS, Sloane NJA &
Stufken J. 1999. Orthogonal Arrays: Theory and
Applications. Springer.
- John JA &
Quenouille MH. 1977. Experiments: Design
and Analysis. Charles & Griffin.
- Khuri AI & Cornell JA. 1996. Response
Surface Designs and Analysis. 2 nd
Ed. Marcel Dekker.
- Montgomery DC. 2005. Design and Analysis of
Experiments. John Wiley.
- Ogawa J. 1974. Statistical Theory of the
Analysis of Experimental Designs. Marcel Dekker.
- Parsad R, Gupta VK, Batra PK, Satpati SK &
Biswas P. 2007. Monograph on α-designs. IASRI, New Delhi.
- Raghavarao D. 1971. Construction and
Combinatorial Problems in Design of Experiments. John Wiley.
- Shah KR & Sinha BK. 1989. Theory of
Optimal Designs. Lecture notes in Statistics. Vol. 54.
Springer.
- Street AP & Street
DJ. 1987. Combinatorics of Experimental
Designs. Oxford Science Publ.
- Design Resources Server:
www.iasri.res.in.
********************************
ADVANCED SAMPLING TECHNIQUES
Objective
- This is an advanced course in Sampling
Techniques that aims at describing some advanced
level topics for students who wish
to pursue research in Sampling Techniques.
This course prepares students for
undertaking research in this area.
This also helps prepare students for
applications of this important subject to Statistical System
in the country.
Theory
- UNIT I
- Controlled selection. Two
way stratification, collapsed strata.
Systematic sampling in two dimensions. Use of combinatorics in
controlled selection. Integration of surveys - Lahiri and Keyfitz's
procedures.
- UNIT II
- Variance estimation in
complex surveys. Taylor's series
linearisation, balanced repeated replication, Jackknife and
bootstrap methods.
- UNIT III
- Unified theory of sampling from finite
populations. UMV - Non-existence theorem and
existence theorem under restricted conditions.
Concept of sufficiency and likelihood
in survey sampling. Admissibility and
hyper- admissibility.
- UNIT IV
- Inference under super
population models - concept of designs
and model unbiasedness, prediction approach. Regression
analysis and categorical data analysis with data
from complex surveys. Domain estimation.
Small area estimation.
- UNIT V
- Stochastic parameter models,
Bayes' linear predictor, Bayesian models
with multi-stage sampling. Measurement error
and small area estimation, Time series
approach in survey sampling. Dynamic
Bayesian prediction, Kalman filter,
Empirical and Hierarchical Bayes predictors,
Robust linear prediction, Bayesian robustness.
Suggested Readings
- Berger JO. 1993.
Statistical Decision Theory and Bayesian
Analysis. Springer.
- Bolfarine H &
Zacks S. 1992. Prediction Theory for
Finite Population Sampling. Springer.
- Cassel CM, Sarndal CE & Wretman JH. 1977.
Foundations of Inference in Survey Sampling. John Wiley.
- Des Raj & Chandhok P. 1998. Sample Survey
Theory. Narosa Publ. House.
- Ghosh M & Meeden
G. 1997. Bayesian Method for Finite
Population Sampling. Monograph on Statistics
and Applied Probability. Chapman &
Hall.
- Mukhopadhyay P. 1998. Theory and Methods of
Survey Sampling. Prentice Hall of India.
- Rao JNK. 2003. Small Area Estimation. John
Wiley.
- Sarndal CE, Swensson B
& Wretman JH. 1992. Model Assisted
Survey Sampling. Springer.
********************************
ADVANCED STATISTICAL GENETICS
Objective
- This is an advanced
course in Statistical Genetics that
aims at describing some advanced level
topics for students who wish to pursue
research in Statistical Genetics. This course prepares
students for undertaking research in this area.
This also helps prepare students for
applications of this important subject in plant and
animal breeding.
Theory
- UNIT I
- Hardy-Weinberg law with
multiple allelic systems, auto-tetraploids
and self-sterility alleles. Complex cases of selection with two or
more loci.
- UNIT II
- Different approaches to
study inbreeding process, methods of
path co- efficient, probability
and generation matrix.
Fisher's approach to inbreeding.
Stochastic process of gene frequency change, transition matrix
approach using finite Markov chains,
diffusion approximation, Steady decay and distribution
of gene frequency, Probability of fixation of a gene, Conditional
process - Markov chains and diffusion approaches, Distribution of
time until fixation, random fluctuations in selection intensity,
stationary distribution of gene frequency. Effective population
size.
- UNIT III
- Prediction and estimation of genetic merit.
Best linear unbiased prediction, Use of mixed model methodology in
analysis of animal and plant breeding experiments. Newer
reproductive technology and its effect
in genetic evaluation of individual merit. Estimation of
genetic parameters - problems relating to
computational aspects of genetic variance
components, parameter estimation in
variance component models for binary
response data.
- UNIT IV
- Identification of genes with large effects,
Use of molecular markers (RFLP, PCR-AFLP, RAPD and
SSR), Gene mapping and Quantitative
trait loci.
- Molecular manipulation for genetic
variability.
- UNIT V
- Survival analysis and concept of censored
observation in animal breeding. Phylogeny and analysis of molecular
variance.
Suggested Readings
- Crow JF & Kimura
M. 1970. An Introduction of Population
Genetics Theory. Harper & Row.
- Ewens WJ. 1979. Mathematical Population
Genetics. Springer.
- Falconer DS. 1985. Introduction to
Quantitative Genetics. ELBL.
- Fisher RA. 1949. The Theory of
Inbreeding. Oliver & Boyd.
- Fisher RA. 1958. The Genetical Theory of
Natural Selection. Dover Publ.
- Haldane JBS. 1932. The Causes of Evolution. Harper
& Bros.
- Kempthorne O. 1957. An Introduction to Genetic
Statistics. The Iowa State Univ. Press.
- Lerner IM.
1950. Population Genetics and
Animal Improvement. Cambridge Univ.
Press.
- Lerner IM. 1958. The Genetic Theory of Selection.
John Wiley.
- Li CC. 1982. Population Genetics. The
University of Chicago Press.
- Mather K & Jinks JL. 1982. Biometrical
Genetics. Chapman & Hall.
- Mather K. 1951. The Measurement of
Linkage in Heredity. Methuen.
- Nagilaki T. 1992. Introduction
to Theoretical Population Genetics.
Springer.
- Narain P. 1990. Statistical Genetics. Wiley
Eastern.
********************************
STATISTICAL MODELING
Objective
- This is an advanced
course in Statistical Methods that aims
at describing some advanced level
topics in this area of research
with a very strong potential of applications. This
course also prepares students for undertaking research
in the area of empirical and
mechanistic models and nonlinear estimation
and the replications in different
disciplines of agricultural sciences.
Theory
- UNIT I
- Empirical and
mechanistic models. Nonlinear growth
models like monomolecular, logistic,
Gompertz, Richards. Applications in
agriculture and fisheries.
- UNIT II
- Nonlinear estimation: Least
squares for nonlinear models, Methods
for estimation of parameters like
Linearization, Steepest, and Levenberg- Marquardt's
Reparameterization.
- UNIT III
- Two-species systems.
Lotka-Volterra, Leslie-Gower and Holling-Tanner
non-linear prey-predator models. Volterra's
principle and its applications. Gause competition
model.
- UNIT IV
- Compartmental modelling -
First and second order input-output
systems, Dynamics of a multivariable system.
Practical
- Fitting of mechanistic non-linear models;
Application of Schaefer and Fox non-linear models; Fitting of
compartmental models.
Suggested Readings
- Draper NR & Smith
H. 1998. Applied Regression Analysis.
3 Ed. John rd Wiley.
- Efromovich S. 1999. Nonparametric Curve
Estimation. Springer.
- Fan J & Yao Q.
2003. Nonlinear Time Series-Nonparametric
and Parametric Methods. Springer.
- France J &
Thornley JHM. 1984. Mathematical Models
in Agriculture. Butterworths.
- Harvey AC. 1996.
Forecasting, Structural Time Series Models
and the Kalman Filter. Cambridge Univ. Press.
- Ratkowsky DA. 1983.
Nonlinear Regression Modelling: A Unified
Practical Approach. Marcel Dekker.
- Ratkowsky DA. 1990. Handbook of Nonlinear
Regression Models. Marcel Dekker.
- Seber GAF & Wild CJ. 1989. Non-linear
Regression. John Wiley.
- Silverman BW. 1986. Density Estimation
for Statistics and Data Analysis. Chapman & Hall.
********************************
ADVANCED TIME SERIES ANALYSIS
Objective
- This is an advanced course in Time Series
Analysis that aims at describing some advanced
level topics in this area of
research with a very strong potential of
applications. This course also prepares students for undertaking
research in this area. This also
helps prepare students for applications
of this important subject to agricultural sciences.
Theory
- UNIT I
- Multivariate time series:
modelling the mean, stationary VAR
models: properties, estimation, analysis and forecasting, VAR models
with elements of nonlinearity,
Non-stationary multivariate time
series: spurious regression, co-integration, common
trends.
- UNIT II
- Volatility: Modelling the variance, The class
of ARCH models: properties, estimation, analysis and forecasting,
stochastic volatility, realized volatility, Extensions:
IGARCH, ARCH-t, ARCD, Multivariate GARCH,
Time- varying risk and ARCH-in-mean.
- UNIT III
- Structural time-series modelling: State space
models, Kalman filter. Local level model, Local linear
trend model, Seasonal models, Cyclical models.
- Nonlinear time-series
models: Parametric and nonparametric
approaches.
- Autoregressive conditional
heteroscedastic model and its
extensions. Threshold and Functional coefficient autoregressive
models.
- UNIT IV
- Nonlinear programming,
Kuhn-Tucker sufficient conditions, Elements
of multiple objective programming, Dynamic Programming,
Optimal control theory - Pontryagin's maximum principle,
Time-optimal control problems.
Suggested Readings
- Box GEP, Jenkins GM
& Reinsel GC. 2008. Time
Series Analysis:
- Forecasting and Control. 3 Ed. John
Wiley. rd
- Brockwell PJ &
Davis RA. 1991. Time Series: Theory
and Methods. 2 nd
Ed. Springer.
- Chatfield C. 2004. The
Analysis of Time Series: An
Introduction. 6 Ed. th Chapman &
Hall/CRC.
- Tong H. 1995.
Nonlinear Time Series: A Dynamical
System Approach. Oxford Univ. Press.
********************************
STOCHASTIC PROCESSES
Objective
- This is a course
on Stochastic Processes that aims at
describing some advanced level topics in this area of research
with a very strong potential of applications. This course also
prepares students for undertaking research in this area. This also
helps prepare students for applications of this important subject to
agricultural sciences.
Theory
- UNIT I
- Introduction to stochastic
process - classification according to
state space and time domain. Finite
and countable state Markov chains;
time- homogeneity; Chapman-Kolmogorov equations,
marginal distribution and finite dimensional
distributions. Classification of Markov chain. Canonical
form of transition probability matrix
of a Markov chain. Fundamental
matrix; probabilities of absorption from
transient states into recurrent classes in a
finite Markov chain, mean time for absorption. Ergodic state
and Ergodic chain. Stationary distribution of a Markov chain, existence
and evaluation of stationary distribution.
Random walk and gamblers ruin
problem.
- UNIT II
- Discrete state continuous
time Markov process: Kolmogorov difference
- differential equations. Birth and
death process, pure birth process
(Yule- Fury process). Immigration-Emigration
process. Linear growth process, pure death
process.
- UNIT III
- Renewal process: renewal
process when time is discrete and
continuous. Renewal function and renewal density. Statements
of Elementary renewal theorem and Key renewal theorem.
- UNIT IV
- Stochastic process in
biological sciences: Markov models in
population genetics, compartmental analysis.
Simple deterministic and stochastic
epidemic model. General epidemic
models-Karmack and McKendrick's threshold theorem.
Recurrent epidemics.
- UNIT V
- Elements of queueing
process; the queuing model M/M/1:
steady state behaviors. Birth and
death process in queuing theory- Multi
channel models. Net work of Markovian queuing system.
- UNIT VI
- Branching process: Galton-Watson branching
process. Mean and variance of size of nth generation,
probability of ultimate extinction of a branching process.
Fundamental theorem of branching process and applications.
- UNIT VII
- Wiener process- Wiener process as a limit of
random walk. First passage time for Wiener process.
Kolmogorov backward and forward
diffusion equations and their applications.
Suggested Readings
- Adke SR & Manjunath SM. 1984. Finite
Markov Processes. John Wiley.
- Bailey NTJ. 1964. Elements of
Stochastic Processes with Applications to the Natural Sciences.
Wiley Eastern.
- Bartlett MS. 1955. Introduction to Stochastic
Processes. Cambridge Univ. Press.
- Basawa IV & Prakasa Rao BLS. 1980.
Statistical Inference for Stochastic Processes. Academic
Press.
- Bharucha-Reid AT. 1960. Elements of the Theory
of Markov Processes and their Applications. McGraw Hill.
- Bhat BR. 2000. Stochastic Models; Analysis and
Applications. New Age.
- Cox DR & Miller
HD. 1965. The
Theory of Stochastic Processes.
Methuen.
- Draper NR & Smith H. 1981. Applied
Regression Analysis. Wiley Eastern.
- France J &
Thornley JHM. 1984. Mathematical Models
in Agriculture.
- Butterworths.
- Karlin S & Taylor
H.M. 1975. A First Course in
Stochastic Processes. Vol. I. Academic Press.
- Lawler GF. 1995. Introduction to Stochastic
Processes. Chapman & Hall.
- Medhi J. 2001. Stochastic Processes.
2 Ed. Wiley Eastern.
- Parzen E. 1962. Stochastic Processes.
Holden-Day.
- Prabhu NU. 1965. Stochastic Processes.
Macmillan.
- Prakasa Rao BLS &
Bhat BR.1996. Stochastic Processes and
Statistical Inference. New Age.
- Ratkowsky DA. 1983.
Nonlinear Regression Modelling: a Unified
Practical Approach. Marcel Dekker.
- Ratkowsky DA. 1990. Handbook of Nonlinear
Regression Models. Marcel Dekker.
- Seber GAF & Wild CJ. 1989. Non-linear
Regression. John Wiley.
********************************
SURVIVAL ANALYSIS
Objective
- The course deals with the study of demographic
profiles and survival times. In-depth statistical
properties and analysis is an
important component of this course.
Theory
- UNIT I
- Measures of Mortality
and Morbidity: Ratios and proportions,
rates of continuous process, rates of
repetitive events ,crude birth rate,
Mortality measures used in vital
statistics relationships between crude and
age specific rates, standardized mortality
ratios ,evaluation of person-year of exposed
to risk in long term studies, prevalence and incidence of a disease,
relative risk and odds ratio.
- Survival Distribution:
Survival functions, hazard rate, hazard
function, review of survival distributions:
exponential, Weibull, Gamma, Rayleigh, Pareto,
Lognormal~ IFR and TFRA, Gompertz and
Makeham. Gompertz and logistic
distributions. Parametric (m.l.e)
estimation. Types of Censoring: Type I,
Type II, random and other types of censoring, right and left
truncated distributions. Expectation and variance
of future life time, series and parallel system of
failures.
- Life Tables: Fundamental and
construction.
- UNIT II
- Complete Mortality data,
Estimation of Survival Function :
Empirical survival function , estimation of survival function from
grouped mortality data, joint distribution of
the number of deaths, distribution
of the estimation P i covariance
of estimate, estimation of curves of
deaths and central death rate and force of mortality rate
.
- Incomplete Mortality data
(non-parametric models): Actuarial method, m.1.e
method, moment and reduced sample method of estimation and their
comparison. Product limit (Kaplan-Meier) method
and cumulative hazard function (CHF) of estimation of
survival function.
- UNIT III
- Fitting Parametric Survival Distribution :
Special form of survival function cumulative hazard
function (CHF) plots, Nelson's method
of ungrouped data, construction of the likelihood function for
survival data, least squares fitting, fitting a Gompertz
distribution to grouped data.
- Some tests of Goodness
of fit: Graphical, Kolmogorov-Smirnov
statistics for complete, censored and truncated data, Chi-Square
test and Anderson- Darling A -statistics.
- Comparison of Mortality Experiences:
Comparison of two life tables, some distribution- free methods (two
samples) for ungrouped data, Two samples Kolmogorov-Smirnov
test, Wilcoxon test for complete data and
modified Wilcoxon test for incomplete
data .Gilbert and Gehan's test, mean
and variance of Wilcoxon statistics, generalization of Gehan's test.
Testing for Consistent Differences in
Mortality : Mantel-Haenszel and log
rank test. Generalized Mantel-Haenszel test
(k-sample).
- UNIT IV
- Concomitant Variables: General parametric
model for hazard function with observed concomitant
variables. Additive and multiplicative
models of hazard rate functions.
Estimating multiplicative models, selection
of concomitant variables. Logistic linear
model, Concomitant Variable regarded
as random variable. Age of onset
distributions: Models of onset distributions and
their estimation.
- Gompertz distribution, parallel system and
Weibull distribution, Fatal short models of failure. Two component
series system.
Suggested Readings
- Anderson B. 1990. Methodological Errors in
Medical Research. Blackwell.
- Armitage P & Berry
G. 1987. Statistical Methods in
Medical Research. Blackwell.
- Collett D. 2003. Modeling Survival Data in
Medical Research. Chapman & Hall.
- Cox DR & Oakes D. 1984. Analysis of
Survival Data. Chapman & Hall.
- Elandt-Johnson RC &
Johnson NL. 1980. Survival Models and
Data Analysis. John Wiley.
- Everitt BS & Dunn G. 1998.
Statistical Analysis of Medical Data. Arnold.
- Hosmer DW Jr. &
Lemeshow S. 1999. Applied Survival
Analysis:
- Regression Modeling or Time to Event. John
Wiley.
- Kalbfleisch JD &
Prentice. RL 2002. The Statistical
Analysis of Failure Time Data. John Wiley.
- Klein JP &
Moeschberger ML. 2003. Survival Analysis:
Techniques for Censored and Truncated Data. Springer.
- Kleinbaum DG & Klein M. 2002. Logistic
Regression. Springer.
- Kleinbaum DG & Klein M. 2005. Survival
Analysis. Springer.
- Lawless JF. 2003.
Statistical Models and Methods for
Lifetime Data. 2 nd Ed. John Wiley.
- Lee ET. 1980.
Statistical Methods for Survival Data
Analysis. Lifetime Learning Publ.
********************************
ADVANCED BIOINFORMATICS
Objective
- This is a course
on Bioinformatics that aims at
exposing the students to some advanced
statistical and computational techniques
related to bioinformatics. This course
would prepare the students in understanding
bioinformatics principles and their applications.
Theory
- UNIT I
- Genomic databases and
analysis of high-throughput data sets,
sequence annotation, ESTs, SNPs. BLAST
and related sequence comparison methods. EM
algorithm and other statistical methods to discover common motifs in
biosequences. Multiple alignment and database search using motif
models, ClustalW and others. Concepts
in phylogeny. Gene prediction based on codons,
Decision trees, Classificatory analysis, Neural Networks, Genetic
algorithms, Pattern recognition, Hidden Markov models.
- UNIT II
- Computational analysis of
protein sequence, structure and
function. Expression profiling by microarray/gene
chip, proteomics etc., Multiple alignment
of protein sequences, Modelling and
prediction of structure of proteins, Designer
proteins, Drug designing.
- UNIT III
- Analysis of one DNA
sequence (Modeling signals in DNA; Analysis
of patterns; Overlaps and Generalizations),
Analysis of multiple DNA or protein
sequences (Alignment algorithms - Gapped global comparisons and
Dynamic programming; use of linear gap
models; protein sequences and substitution
matrices - BLOSUM, PAM; Multiple
sequences), BLAST (Comparison of two aligned sequences -
Parameter calculation; Choice of a score; Bounds
for P-value; Normalized and Bit
scores, Karlin - Altschul sum
statistic; comparison of two
unaligned sequences; Minimum
significance Lengths).
- UNIT IV
- Markov chains (MC with
no absorbing states; Higher order
Markov dependence; patterns in sequences; Markov chain Monte
Carlo - Hastings- Metropolis algorithm, Gibbs
sampling, Simulated Annealing; MC with
absorbing States, Continuous-Time Markov
chains) Hidden Markov Models (Forward and
Backward algorithm; Viterbi algorithms; Estimation
algorithm;
- UNIT V
- Modeling protein families;
Multiple sequence alignments; Pfam; Gene
finding), Computationally intensive
methods (Classical estimation methods;
Bootstrap estimation and Confidence
Intervals; Hypothesis testing; Multiple
Hypothesis testing), Evolutionary models
(Models of Nucleotide substitution; Discrete
time models - The Jukes-Cantor Model,
- The Kimura Model, The Felsenstein Model;
Continuous-time models),
- UNIT VI
- Phylogenetic tree estimation (Distances; Tree
reconstruction - Ultrametric and Neighbor-Joining
cases; Surrogate distances; Tree
reconstruction; Parsimony and
Maximum Likelihood; Modeling,
Estimation and
- Hypothesis Testing;) Neural
Networks (Universal Approximation Properties;
Priors and Likelihoods, Learning Algorithms
- Backpropagation; Sequence encoding and output
interpretation; Prediction of Protein Secondary
Structure; Prediction of Signal Peptides
and their cleavage sites; Application
for DNA and RNA Nucleotide Sequences),
Analysis of SNPs and Haplotypes.
Suggested Readings
- Baldi P & Brunak
S. 2001. Bioinformatics: The Machine
Learning Approach. MIT Press.
- Baxevanis AD &
Francis BF. (Eds.). 2004. Bioinformatics:
A Practical Guide to the Analysis of Genes and Proteins. John
Wiley.
- Duda RO, Hart PE & Stork DG. 1999. Pattern
Classification. John Wiley.
- Ewens WJ & Grant
GR. 2001. Statistical Methods in
Bioinformatics. Springer.
- Jones NC & Pevzner PA. 2004. Introduction
to Bioinformatics Algorithims. The MIT Press.
- Koskinen T. 2001. Hidden Markov Models for
Bioinformatics. Kluwer.
- Krane DE & Raymer ML. 2002. Fundamental
Concepts of Bio-informatics. Benjamin / Cummings.
- Krawetz SA &
Womble DD. 2003. Introduction to
Bioinformatics: A Theoretical and Practical Approach. Humana
Press.
- Lesk AM. 2002. Introduction to
Bio-informatics. Oxford Univ. Press.
- Linder E & Seefeld K. 2005. R for
Bioinformatics. O'Reilly & Associates. Percus JK. 2001.
Mathematics of Genome Analysis. Cambridge
Univ. Press.
- Sorensen D & Gianola
D. 2002. Likelihood, Bayesian and
MCMC Methods in Genetics. Springer.
- Tisdall JD. 2001.
Mastering Perl for Bioinformatics. O'Reilly
& Associates.
- Wang JTL, Zaki MJ,
Toivonen HTT & Shasha D. 2004.
Data Mining in Bioinformatics. Springer.
- Wu CH & McLarty JW. 2000. Neural Networks
and Genome Informatics. Elsevier.
- Wunschiers R. 2004. Computational Biology
Unix/Linux, Data Processing and Programming. Springer.
- Yang MCC. 2000. Introduction to Statistical
Methods in Modern Genetics.
- Taylor & Francis.
********************************
ADVANCED ECONOMETRICS
Objective
- This is a course on Econometrics aims at
exposing the students to some advanced level econometric
methods and their applications to agricultural
situations.
Theory
- UNIT I
- Quantile regression, binary
quantile regression, extreme values, copula,
loss functions, Point and interval forecasting, unconditional and
conditional forecasting, forecasting
with serially correlated
errors, bootstrap: asymptotic expansion, bootstrap
consistency, asymptotic refinement, recent developments for
dependent time series
- UNIT II
- Multivariate time series:
modelling the mean, stationary VAR
models: properties, estimation, analysis and forecasting, VAR models
with elements of nonlinearity, Non-stationary
multivariate time series:
spurious regression, co-integration, common
trends; Volatility: Modelling the variance, The
class of ARCH models: properties, estimation, analysis and
forecasting, stochastic volatility, realized volatility.
- UNIT III
- Basic Concepts of Bayesian Inference,
Probability and Inference, Posterior Distributions and Inference,
Prior Distributions. The Bayesian linear model and
autoregressive (AR) processes; Model selection
with marginal likelihoods and fractional
priors, Comparison of Bayesian Methods
with Classical approaches, Bayes risk
and their applications, and Sample
Selection Monte Carlo integration, importance
sampling and Gibbs sampling, The
Regression Model with General Error
Covariance Matrix, Qualitative Choice Models, Bayesian
information criterion (BIC), Markov Chain Monte
Carlo (MCMC) Model Composition and
stochastic search variable selection, BUGS
[Bayesian Inference Using Gibbs Sampling]
, BUCC [Bayesian Analysis, Computation and Communication].
Technometrics
Suggested Readings
- Banerjee A, Dolado J,
Galbraith J & Hendry DF. 1993.
Co-integration,
- Error Correction, and the Econometric Analysis
of Nonstationary Data. Oxford Univ. Press.
- Bauwens L, Lubrano M
& Richard JF. 1999. Bayesian
Inference in Dynamics of Econometric Models. Oxford Univ.
Press.
- Carlin BP & Louis
TA. 1996. Bayes and Empirical Bayes
Methods for Data Analysis. Chapman & Hall.
- Gilks WR, Richardson S
& Spiegelhalter D. 1996. MCMC in
Practice. Chapman & Hall.
- Greenberg E. 2008.
Introduction to Bayesian Econometrics. Cambridge
Univ. Press.
- Hamilton JD. 1994. Time Series Analysis.
Princeton Univ. Press.
- Judge GG, Griffith WE,
Hill RC, Lee CH & Lutkepohl
H. 1985. The Theory and Practice of Econometrics. 2 Ed.
John Wiley.
- Koop G, Poirier D
& Tobias J. 2007. Bayesian Econometric
Methods. Cambridge Univ. Press.
- Koop G. 2003. Bayesian Econometrics. John
Wiley.
- Lancaster A. 2004.
An Introduction to Modern Bayesian
Econometrics. Blackwell.
- Pindyck RS &
Rubinfeld DL. 1981. Econometric Models
and Economic Forecasts. McGraw Hill.
********************************
RECENT ADVANCES IN THE FIELD OF SPECIALIZATION
Objective
- To familiarize the
students with the recent advances in
the areas of their specialization to prepare them
for undertaking research.
- Theory
- Recent advances in the field of specialization
- sample surveys / design of experiments /statistical
genetics / statistical modeling /
econometrics / statistical inference, etc.
will be covered by various speakers from
the University / Institute as well as from outside the University /
Institute in the form of seminar talks.
List of Journals
Agricultural Statistics
- American Statistician
- Annals of Institute of Statistical
Mathematics
- Annals of Statistics
- Australian and New Zealand Journal of
Statistics
- Biometrical Journal
- Biometrics
- Biometrika
- Bulletin of Calcutta Statistical
Association
- Canadian Journal of Statistics
- Communication in Statistics (Simulation &
Computation)
- Communication in Statistics ( Theory & and
Methods)
- Experimental Agriculture
- Institute of Mathematical Statistics Bulletin
(IMSB)
- Journal of American Statistical
Association
- Journal of Applied Statistics
- Journal of the Indian Society of Agricultural
Statistics
- Journal of the International Statistical
Review
- Journal of Statistical Planning and
Inference
- Journal of Statistical Theory and
Practice
- Journal of Statistics, Computer and
Applications
- Journal of Royal Statistical Society, Series
A
- Journal of Royal Statistical Society, Series
B
- Journal of Royal Statistical Society, Series
C
- Metrika
- Metron
- Scandinavian Journal of Statistics (Theory
& Applied)
- Sankhya
- Statistica
- Statistical Science
- Statistics and Probability Letters
- Technometrics
Computer Application
- ACM Transactions on Knowledge Discovery from
Data
- Applied Intelligence - The International
Journal of Artificial Intelligence, Neural Networks, and Complex Problem-Solving
Technologies
- Computational Statistics & Data Analysis,
Elsevier Inc.
- Computers and Electronics in Agriculture,
Elsevier Inc.
- Data Mining and Knowledge Discovery: An
International Journal (DMKD)
- Expert Systems with Applications, Elsevier Inc.
- IEEE Transactions on Knowledge and Data
Engineering
- IEEE Transactions on Neural Networks
- IEEE Transactions on Pattern Analysis and
Machine Intelligence
- International Journal of Computing and
Information Sciences
- International Journal of Information and
Management Sciences
- International Journal of Information
Technology
- Journal of Artificial Intelligence
Research
- Journal of Combinatorics, Information and
System Sciences
- Journal of Computer Sciences and
Technology
- Journal of Computer Society of India
- Journal of Indian Society of Agricultural
Statistics
- Journal of Intelligent Information Systems -
Integrating Artificial Intelligence and Database Technologies
- Journal of Machine Learning Research
- Journal of Statistics, Computer and
Applications
- Journal of Systems and Software
- Journal of Theoretical and Applied Information
Technology
- Knowledge and Information Systems: An
International Journal (KAIS)
- Lecture Notes in Computer Science, Springer
Verlag.
- Machine Learning
- Transactions on Rough Set
e-Resources
- Design Resources Server. Indian Agricultural
Statistics Research Institute(ICAR), New Delhi 110 012, India.
www.iasri.res.in/design.
- Design Resources: www.designtheory.org
- Free Encyclopedia on Design of
Experiments
- http://en.wikipedia.org/wiki/Design_of_experiments
- Statistics Glossary http://www.cas.lancs.ac.uk/glossary_v1.1/main.html.
- Electronic Statistics Text Book:
http://www.statsoft.com/textbook/stathome.html.
- Hadamard Matrices
http://www.research.att.com/~njas/hadamard;
- Hadamard Matrices
http://www.uow.edu.au/~jennie/WILLIAMSON/williamson.html.
- Course on Experimental design:
http://www.stat.sc.edu/~grego/courses/stat706/.
- Learning Statistics:
http://freestatistics.altervista.org/en/learning.php.
- Free Statistical Softwares:
http://freestatistics.altervista.org/en/stat.php.
- Statistics Glossary
http://www.cas.lancs.ac.uk/glossary_v1.1/main.html.
- Statistical Calculators:
http://www.graphpad.com/quickcalcs/index.cfm
- SAS Online Doc 9.1.3:
http://support.sas.com/onlinedoc/913/docMainpage.jsp
********************************
Suggested Broad Topics for Research
Agricultural Statistics
- Design and analysis of multi-response
experiments
- Design and analysis of micro-array
experiments
- Design and analysis of experiments for
precision agriculture
- Design and analysis of agroforestry
experiments
- Bayesian designing of experiments, Bayesian
optimality and Bayesian analysis of experimental data
- Computer aided search of efficient
experimentaldesigns for various experimental settings
- Fractional factorials including search
designs, supersaturated designs, computer experiments, etc.
- Statistical techniques in bioinformatics,
biotechnology, microbiology, genomics, etc.
- Optimality aspects and robustness of designs
against several disturbances unde various experimental settings (single
factor, multi-factor, nested classifications, etc.)
- Small area estimation
- Computer intensive techniques in sample
surveys
- Analysis of survey data, regression analysis,
categorical data analysis, analysis of complex survey data
- Assessment and impact survey
methodologies,valuation of natural resources, its degradation, depletion,
etc.
- Linear and non-linear modeling of biological
and economical phenomena
- Non-linear time series modeling
- Non-linear stochastic modeling
- Forecast models for both temporal and spatial
data
- Innovative applications of resampling
techniques
- Applications of remote sensing, GIS, ANN etc.
in modeling various phenomena
- Econometric models for risk,
uncertainty, insurance, market analysis, technical efficiency,
policy planning, etc.
- Statistical studies on value addition to crop
produce
Computer Application
- Web solutions in agriculture
- Decision Support/Expert Systems/Information
Management Systems in Agriculture
- Software for Statistical Data Analysis
- Modelling and Simulation of Agricultural
Systems
- Application Software for GIS and Remote Sensing
- Office Automation and Management System
********************************
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